Evidence map›Paper›PMID 41305886›Full record

ArticleJournal of cardiovascular electrophysiology2026

Outcomes of Focused Double Extrastimuli Mapping and Ablation in Ventricular Tachycardia.

Surachat Jaroonpipatkul, Andrea N Keithler, Thipsukhon Sathapanasiri, Harikrishna Tandri, T Jared Bunch, Ravi Ranjan, Klitos Konstantinidis

Abstract readComparative Study
In one paragraph

Article in Journal of cardiovascular electrophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Surachat JaroonpipatkulDivision of Cardiovascular Medicine, University of Utah Health, Salt Lake City, Utah, USA.ORCID 0000-0003-0200-848X
Andrea N KeithlerDivision of Cardiovascular Medicine, University of Utah Health, Salt Lake City, Utah, USA.
Thipsukhon SathapanasiriDepartment of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA.
Harikrishna TandriDivision of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
T Jared BunchDivision of Cardiovascular Medicine, University of Utah Health, Salt Lake City, Utah, USA.
Ravi RanjanDivision of Cardiovascular Medicine, University of Utah Health, Salt Lake City, Utah, USA.
Klitos KonstantinidisDivision of Cardiovascular Medicine, University of Utah Health, Salt Lake City, Utah, USA.

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

backgroundConventional substrate mapping for scar-related ventricular tachycardia (VT) often fails to fully delineate critical arrhythmogenic components. Functional mapping strategies using extrastimuli have shown promise but are limited by procedural complexity.

methodsIn total, 57 patients undergoing VT ablation between March 2023 and October 2024 were included in the study. Patients were grouped based on whether targeted double extrastimuli mapping (focused DEMAP) was used to guide mapping and ablation. Mapping was performed using EnSite X with omnipolar technology. Clinical and procedural outcomes were compared between focused DEMAP and non-DEMAP groups with outcomes follow-up at 12 months.

resultsFocused DEMAP revealed a significantly higher correlation between DZs and VT critical isthmuses compared to sinus rhythm mapping (75.9% vs. 37.1%, p = 0.01). VT-free survival at 12 months was higher in the DEMAP group (88.03%) than in the non-DEMAP group (58.10%, p = 0.04). Trends also favored DEMAP in reducing cardiovascular hospitalization (10.55% vs. 24.70%) and mortality, though not statistically significant. Overall procedure time was similar mainly driven by less time during ablation and a lower mean ablated area in the focused DEMAP group compared to the non-DEMAP group.

conclusionThe focused DEMAP, a focused double extrastimulus mapping strategy, enhances VT substrate identification and is associated with improved VT-free survival without prolonging procedure time. This approach may refine substrate-based ablation and optimize lesion targeting without increasing procedural burden.

Indexed as

Action PotentialsCatheter AblationElectrophysiologic Techniques, CardiacHeart RateTachycardia, VentricularAdultAgedFemaleHumansMaleMiddle AgedPredictive Value of TestsProgression-Free SurvivalRetrospective StudiesRisk FactorsTime Factors

Identifiers

PMID41305886
PMCPMC12794788

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.