Evidence map›Paper›PMID 41305832›Full record

Observational studyMedicine2025

Analysis of risk factors for recurrence of Budd-Chiari syndrome: A retrospective study with zero-inflated model.

Shengli Li, Xiangting Liu, Muyao Zhou, Cuocuo Wang, Hui Wang, Qingqiao Zhang, Lei Wang, Yong Zhou

Abstract readObservational Study
In one paragraph

Observational study in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shengli LiClinical Research Institute, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.ORCID 0000-0002-2612-0655
Xiangting LiuDepartment of Geriatrics, Xuancheng People's Hospital, Xuancheng, Anhui, China.ORCID 0000-0002-2334-5189
Muyao ZhouJiangsu Normal University, Xuzhou, Jiangsu, China.ORCID 0009-0009-9396-1217
Cuocuo WangDepartment of Geriatrics, Xuancheng People's Hospital, Xuancheng, Anhui, China.
Hui WangDepartment of Hepatobiliary Surgery, Xuzhou Central Hospital, Xuzhou, Jiangsu, China.
Qingqiao ZhangDepartment of Interventional Radiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
Lei WangSchool of Computer Science and Technology/School of Artificial Intelligence, China University of Mining and Technology, Xuzhou, Jiangsu, China.ORCID 0000-0003-0184-307
Yong ZhouSchool of Computer Science and Technology/School of Artificial Intelligence, China University of Mining and Technology, Xuzhou, Jiangsu, China.

Funding

Advanced Program of The Affiliated Hospital of Xuzhou Medical University PYJH2025203Construction Project of High Level Hospital of Jiangsu Province GSPSJ20240805Medical Technology Innovation Project of the Xuzhou Municipal Health Commission XWKYHT20230072the Postgraduate Research & Practice Innovation Program of Jiangsu Province SJCX22_1276
6 · The paper itself

Abstract

This study aims to identify an optimal model for assessing the recurrence frequency of Budd-Chiari syndrome (BCS) and further analyze the factors contributing to BCS recurrence. A total of 754 patients who were admitted to the Affiliated Hospital of Xuzhou Medical University between January 2015 and July 2022 were included. We constructed 4 different count outcome models: Poisson, negative binomial (NB) model, zero-inflated Poisson (ZIP) model, and zero-inflated negative binomial (ZINB) model. We selected the model with the best fitting performance to explore factors associated with BCS recurrence. Of 754 respondents, 511 reported no recurrence. Log-likelihood ratio tests indicated that the NB model performed better than the Poisson regression model (χ2 = 124.91, P < .001), and the ZINB model outperformed the ZIP model (χ2 = 34.29, P < .001). In the ZINB model, the analysis of the counting process revealed that the variables significantly associated with recurrence frequency included age (odds ratio [OR] = 0.69; 95% confidence interval [CI]: 0.57-0.84), sex (female: OR = 1.77; 95% CI: 1.24-2.55), anticoagulant use (warfarin vs new oral anticoagulants [NOACs]: OR = 2.11, 95% CI: 1.34-3.31; not using anticoagulants vs NOACs: OR = 1.98, 95% CI: 1.20-3.28), absence of cirrhosis (OR = 0.57, 95% CI: 0.40-0.82), and neutrophil count (NEU) (OR = 1.22, 95% CI: 1.04-1.42). The zero-inflated model proved robust in identifying factors influencing BCS recurrence compared with the other models. Influence of sex, surgery, anticoagulation, cirrhosis, hospital duration, apolipoprotein A, and NEU on the recurrence risk and frequency of BCS.

Indexed as

Budd-Chiari SyndromeModels, StatisticalAdultAgedAge FactorsAnticoagulantsChinaFemaleHumansMaleMiddle AgedRecurrenceRetrospective StudiesRisk FactorsSex FactorsAnticoagulantsBudd–Chiari syndromedispersionrecurrenceZINB regression

Identifiers

PMID41305832
PMCPMC12643598

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.