Evidence map›Paper›PMID 41305828›Full record

Trial reportMedicine2025

Effect of low-frequency repetitive transcranial magnetic stimulation combined with motor imagery training on upper limb motor recovery and primary motor cortex activation in stroke patients: A randomized controlled trial.

Jong-Bae Choi, Seo-Won Yang, Ji-Su Park

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jong-Bae ChoiDepartment of Occupational Therapy, Chosun University, Gwangju, Republic of Korea.
Seo-Won YangDepartment of Occupational Therapy, Doowon Technical University, Gyeonggi-do, Republic of Korea.
Ji-Su ParkResearch Institute for Korean Medicine, Pusan National University, Yangsan, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to investigate the effects of low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) combined with motor imagery training (MIT) on upper limb function recovery and primary motor cortex (M1) activation in patients with stroke.

methodsForty-four patients with stroke were randomly assigned into 2 groups: experimental (both LF-rTMS combined with MIT, N = 22), and control (LF-rTMS, N = 22) groups. The treatment was performed for 20 minutes a day, 3 days a week, for 8 weeks. To evaluate upper limb function, the Fugl-Meyer assessment for upper extremity, wolf motor function test, and action research arm test were conducted. To evaluate M1 activation, motor-evoked potential amplitude was evaluated before and after conducting the study.

resultsThe results indicated that both groups showed significant changes across all evaluation items before and after the intervention. In the prepost and change comparisons, the experimental group demonstrated significantly greater changes in the FMA-UE, wolf motor function test, and action research arm test than the control group. Moreover, the combined intervention of LF-rTMS and MIT was effective in improving upper limb function and activating M1 in patients with severe stroke.

conclusionWe propose this intervention as a novel clinical intervention method for recovering upper limb function in patients with stroke.

Indexed as

Imagery, PsychotherapyMotor CortexStrokeStroke RehabilitationTranscranial Magnetic StimulationUpper ExtremityAdultAgedEvoked Potentials, MotorFemaleHumansMaleMiddle AgedRecovery of FunctionTreatment Outcomelow-frequency repetitive transcranial magnetic stimulationmotor imagery trainingprimary motor cortex activationstrokeupper limb function

Identifiers

PMID41305828
PMCPMC12643587

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.