Evidence map›Paper›PMID 41305827›Full record

SynthesisMedicine2025

Flexible negative pressure suction ureteral access sheath combined with ureteroscopy in the treatment of upper urinary tract calculi: A meta-analysis.

Huanglin Duan, Baisheng Xu, Tianpeng Xie

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Huanglin DuanDepartment of Urology, The First People's Hospital of Xiushui County, Jiujiang, Jiangxi, China.ORCID 0009-0002-6464-3390
Baisheng XuDepartment of Urology, The First People's Hospital of Xiushui County, Jiujiang, Jiangxi, China.
Tianpeng XieDepartment of Urology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.ORCID 0000-0001-5038-3677

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUpper urinary tract stones are common diseases in urology. Ureteroscopic lithotripsy is one of the main methods for the treatment of upper urinary tract stones. With the rise of flexible urinary tract examination (F-UAS), it makes surgery safer and more effective. This study aims to compare the safety and effectiveness of flexible ureteral access sheath and traditional ureteral access sheath when used with ureteroscopic lithotripsy for treating upper urinary tract stones.

methodsA systematic search was conducted on PubMed, Embase, cochrane library, scopus, and web of science databases for studies that evaluated the use of F-UAS in treating upper urinary tract stones. The outcome measures assessed in this study included operation time, immediate stone-free rate (SFR), 1-month postoperative follow-up SFR, postoperative complication rate, postoperative fever rate, and hospital stay after surgery.

resultsThis study included 9 studies involving 1769 patients, with 907 in the experimental group and 862 in the control group. The meta-analysis revealed no significant difference in operation time between the experimental and control groups (MD = 4.73, 95% confidence interval [CI]: -2.41 to 11.86, P = .19). The experimental group demonstrated higher immediate SFR (OR = 3.84, 95% CI: 1.56-9.42, P = .003) and postoperative follow-up SFR (OR = 2.60, 95% CI: 1.61-4.20, P < .0001). Additionally, the incidence of postoperative complications was lower in the experimental group (OR = 0.47, 95% CI: 0.30-0.74, P = .001), as was the incidence of fever (OR = 0.27, 95% CI: 0.16-0.45, P < .00001). Furthermore, the postoperative hospital stay was shorter for the experimental group than the control group (MD = -0.09, 95% CI: -0.16 to 0.01, P = .02). No significant differences were observed in stone size (MD = 0.20, 95% CI: -0.13 to 0.53, P = .24) and age between the 2 groups (MD = 0.30, 95% CI: -0.88 to 1.47, P = .62).

conclusionCompared to traditional ureteral access sheath, applying negative pressure suction with F-UAS for treating upper urinary tract calculi has enhanced stone clearance rates, expedited patient discharge, and decreased postoperative complications. Consequently, F-UAS may represent a superior option for retrograde internal surgery in clinical practice.

Indexed as

Kidney CalculiLithotripsyUreteral CalculiUreteroscopyUrinary CalculiHumansLength of StayOperative TimePostoperative ComplicationsSuctionTreatment Outcomeflexible ureteral access sheathretrograde intrarenal surgeryupper urinary tract stonesureteroscope

Identifiers

PMID41305827
PMCPMC12643778

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.