Evidence map›Paper›PMID 41305818›Full record

Observational studyMedicine2025

Resuscitation and survival time in terminal cancer patients at the end of life: A retrospective observational study in a Chinese hospital.

Zhongping Yao, Hongxia Tan, Yuehe Tu, Shaowen Wang, Lixin Qu, Xiang Li

Abstract readObservational Study
In one paragraph

Observational study in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhongping YaoRadiotherapy Department Ⅱ, Jinshazhou Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Hongxia TanCenter for Reproductive Medicine, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China.
Yuehe TuFifth Department of Oncology, Jinshazhou Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Shaowen WangIntervention Center, Jinshazhou Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Lixin QuFifth Department of Oncology, Jinshazhou Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Xiang LiFifth Department of Oncology, Jinshazhou Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.ORCID 0000-0002-8972-865

Funding

Guangzhou City Health Technology Project 2024A011031
6 · The paper itself

Abstract

End-of-life care decisions for terminal cancer patients remain a clinical and ethical challenge, particularly regarding the use of aggressive interventions. This retrospective observational study aimed to evaluate the impact of different treatment schemes on survival time in terminal cancer patients. A total of 1266 patients were categorized into 4 groups: Group A received mechanical assistance and other rescue measures in the intensive care unit (ICU); Group B received drug rescue with cardiopulmonary resuscitation in the general ward; Group C received drug rescue only; and Group D received no rescue treatment. Overall survival was estimated using Kaplan-Meier analysis, and between-group differences were assessed with stratified log-rank tests. The median survival times were: Group A: 138.0 hours (95% confidence interval [CI]: 109.1-166.8), Group B: 54.5 hours (95% CI: 42.8-66.3), Group C: 60.0 hours (95% CI: 51.7-68.3), and Group D: 60.4 hours (95% CI: 53.9-66.8). Group A showed significantly longer survival than Groups B, C, and D (P < .05), whereas no significant difference was observed among Groups B, C, and D (P > .05). ICU-based resuscitation may provide modest survival benefit for terminal cancer patients, whereas drug-based rescue and cardiopulmonary resuscitation outside the ICU do not appear to extend survival. These findings support individualized, evidence-based decision-making for end-of-life interventions.

Indexed as

Cardiopulmonary ResuscitationNeoplasmsResuscitationTerminal CareAdultAgedChinaFemaleHumansIntensive Care UnitsKaplan-Meier EstimateMaleMiddle AgedRetrospective Studiescardiopulmonary resuscitation (CPR)end-of-life careintensive care unit (ICU)survival analysisterminal cancer

Identifiers

PMID41305818
PMCPMC12643739

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.