ReviewMedicine2025
Intraplaque neovascularization and progression of atherosclerosis: A review of SMI technical assessment and berberine-statin regulatory mechanisms.
Review in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Intraplaque neovascularization (IPN) is a central driver of atherosclerosis (AS) progression and plaque vulnerability, and its dynamics are closely related to the risk of cardiovascular events. Superb microvascular imaging (SMI) has become a key tool for IPN assessment due to its noninvasive and highly sensitive characteristics, and the combination of berberine and statins has demonstrated significant synergistic effects in regulating IPN and stabilizing plaques. This article describes the pathological mechanisms of IPN in the progression of AS, summarizes the value of SMI technology and multimodal imaging in the assessment of IPN, and analyzes the molecular mechanisms and clinical evidence of berberine and statins in the regulation of IPN, so as to provide an integrated "assessment-intervention" basis for the precise prevention and treatment of AS.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.