Evidence map›Paper›PMID 41305769›Full record

Observational studyMedicine2025

Quality of life and surgical outcomes of endoscopic thyroidectomy versus open thyroidectomy in papillary thyroid carcinoma.

Miaofeng Wang, Guoping Jin

Abstract readComparative StudyObservational Study
In one paragraph

Observational study in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Miaofeng WangDepartment of General Surgery, Shaoxing Central Hospital (The Central Affiliated Hospital, Shaoxing University), Shaoxing, Zhejiang Province, China.ORCID 0009-0003-9393-9251
Guoping JinDepartment of Medicine, Shaoxing Keqiao District Women & Children's Hospital, Shaoxing, Zhejiang Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endoscopic thyroidectomy (ET) avoids larger neck incisions. It offers superior cosmetic outcomes and improves patient satisfaction. However, the effect of ET on quality of life (QoL) remains incompletely investigated. This study was therefore designed to compare QoL and key surgical outcomes between ET and conventional open thyroidectomy (OT) in patients diagnosed with papillary thyroid carcinoma. This retrospective analysis enrolled 667 patients with papillary thyroid carcinoma who underwent thyroidectomy. To mitigate potential confounding factors, propensity score matching was applied, resulting in a final cohort of 44 ET patients and 66 OT patients for comparative analysis. The SF-36 and thyroid surgery-specific questionnaires were used to assess QoL, overall satisfaction, surgical and cosmetic outcomes at 15, 30, and 60 days postoperatively. Patients in the ET group generally exhibited higher SF-36 QoL scores than those in the OT group across several parameters. Thyroid surgery-specific questionnaires indicated lower swallowing discomfort in the ET group (P < .05). Significant differences were observed in operating time (P < .001), cosmetic outcomes (P < .001), hospital costs (P < .001), and overall satisfaction (P < .001). The ET group included a higher proportion of higher educated individuals (P < .05). No significant intergroup differences were observed in terms of postoperative drainage, visual analogue scale pain scores, length of hospital stay, or complication rates. ET offers comparable safety to OT, along with superior QoL and cosmetic outcomes, making it a viable alternative for both patients and surgeons.

Indexed as

EndoscopyQuality of LifeThyroid Cancer, PapillaryThyroidectomyThyroid NeoplasmsAdultCarcinoma, PapillaryFemaleHumansMaleMiddle AgedOperative TimePatient SatisfactionPostoperative ComplicationsPropensity ScoreRetrospective Studiesendoscopicpapillary thyroid carcinomaquality of lifethyroidectomy

Identifiers

PMID41305769
PMCPMC12643636

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.