Evidence map›Paper›PMID 41305762›Full record

ArticleMedicine2025

Knowledge mapping of Cushing syndrome: A bibliometric analysis from 2000 to 2023.

Xiao Lu, Mingyu Huang, Yufang Yang, Dongxiao Chen, Fuli Qin, Quanyuan Huang

Abstract read
In one paragraph

Article in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiao LuDepartment of Pharmacy, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China.
Mingyu HuangGuangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China.
Yufang YangDepartment of Pharmacy, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China.
Dongxiao ChenAffiliated Hospital of Yulin City Health School, Yulin, Guangxi Zhuang Autonomous Region, China.
Fuli QinDepartment of Pharmacy, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China.
Quanyuan HuangDepartment of Pharmacy, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China.ORCID 0009-0005-0765-4407

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCushing syndrome (CS) is an endocrine disorder primarily caused by cortisol overproduction, resulting in a range of clinical manifestations. Although recent studies have advanced the understanding and treatment of CS, no comprehensive bibliometric analysis has yet mapped the development and trends in this field. This study aimed to provide a detailed overview of the knowledge landscape, research output, and emerging hotspots in CS research using bibliometric methods.

methodsA bibliometric analysis was conducted using publications on CS indexed in the Web of Science Core Collection from January 2000 to October 2023. VOSviewers, CiteSpace, and the R package bibliometrix were used to analyze publication outputs, author collaborations, institutional and country-level contributions, journal impact, co-citation networks, and keyword trends.

resultsThe volume of CS-related publications has shown a steady annual increase. A total of 4661 articles were published across 86 countries. The United States produced the highest number of publications, while the Eunice Kennedy Shriver National Institute of Child Health and Human Development ranked as the most active institution. The Journal of Clinical Endocrinology and Metabolism was the leading source both in terms of publication count and co-cited frequency. The 19,621 contributing authors included several high-output researchers, notably Constantine A Stratakis, Martin Reincke, Jerome Bertherat, Susan M. Webb, and Felix Beuschlein. Keywords analysis identified "11β-hydroxylase inhibitors" and "somatic mutation" as prominent emerging topics.

conclusionThis bibliometric study presents the first comprehensive mapping of global CS research over the past 2 decades. It identifies influential contributors, collaborative networks, and thematic developments, offering a structured reference for future research planning and scholarly engagement in the field of CS.

Indexed as

BibliometricsCushing SyndromeHumans11β-hydroxylase inhibitorbibliometric analysisCitespaceCushing syndromesomatic mutationVOSviewer

Identifiers

PMID41305762
PMCPMC12643767

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.