ArticleMedicine2025
Bibliometric analysis of the correlation between aflatoxin and hepatic carcinoma.
Article in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Climate-Driven Aflatoxin MToxins · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
backgroundAflatoxin serves as a distinct risk factor for hepatic carcinoma, making the investigation into its association with hepatic carcinoma is essential for unraveling the molecular underpinnings of oncogenesis and devising therapeutic strategies for tumors. However, the mechanism by which aflatoxin causes liver cancer is not yet clear. This article aims to analyze the latest research progress and cutting-edge exploration directions for aflatoxin-induced liver cancer.
methodThis research relies on the Web of Science core collection for information retrieval, leveraging the broad scope of the SCI-EXPANDED index to guarantee comprehensiveness and high precision of the gathered data. From April 30, 2014 to April 30, 2024, relevant original research literature and reviews on aflatoxin and liver cancer were retrieved. Subsequently, VOSviewer, CiteSpace, and R software were used to visualize and analyze the articles.
resultsA total of 597 relevant studies were obtained, with 3228 authors from 1116 organizations in 94 countries. America and China are major contributors to international publications. Groopman, John D has the most publications, and Jessica Zucman-Rossi has the highest number of citations. Guangxi Medical University, China Agricultural University, Johns Hopkins University, etc were the main research institutions. Toxins, Food and Chemical Toxicology are popular journals in this field, and the most cited journal is Nature Reviews Gastroenterology & Hepatology. Research primarily focuses on 4 areas: the correlation between aflatoxin contamination, exposure levels, and the progression of hepatic carcinoma; the underlying processes by which aflatoxin inflicts liver injury that may result in hepatic carcinoma; the combined impact of aflatoxin B1 and the hepatitis B virus (HBV) on the onset of hepatic carcinoma; and strategies for the prevention and management of aflatoxin-induced hepatic malignancies. Specifically, aflatoxins can induce hepatotoxicity, immunotoxicity, alter expression of coding genes and noncoding RNAs, and synergize with hepatitis B virus to promote hepatocarcinogenesis. Physical, chemical, and biological methods have been widely employed to degrade aflatoxins for liver cancer prevention and control, among which biological control have garnered significant attention from researchers.
conclusionResearch on the aflatoxin-hepatic carcinoma link is rapidly advancing. Furthermore, it confirms aflatoxin's pivotal role in the pathogenesis of liver cancer.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.