Evidence map›Paper›PMID 41305668›Full record

ReviewNutrients2025

Future Directions in Choline: From Neurodevelopment to Cardiometabolic Health.

Evan M Paules, Hannah G Petry, Jessica K Sprinkles, Isis Trujillo-Gonzalez

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Evan M PaulesNutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, NC 28081, USA.ORCID 0000-0002-8344-818X
Hannah G PetryNutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, NC 28081, USA.ORCID 0009-0007-5187-7792
Jessica K SprinklesNutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, NC 28081, USA.ORCID 0009-0003-5731-7324
Isis Trujillo-GonzalezNutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, NC 28081, USA.ORCID 0000-0002-4239-4795

Funding

Nutrigenetic analysis of choline status biomarkersR01DK115380 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ZEISEL, STEVEN H · 2018 to 2021
$2.8M
NIDDK NIH HHS R01 DK115380Nutrition Research Institute, start up to I. T-G N/A
6 · The paper itself

Abstract

Although choline was established as an essential nutrient over three decades ago, critical questions remain about how choline regulates brain, liver, and cardiometabolic health across the lifespan. This Perspective summarizes emerging insights presented at the

Indexed as

Cardiovascular DiseasesCholineAnimalsBrainCognitionDietary SupplementsFemaleHumansMethylaminesObesityPregnancyCholineMethylaminestrimethyloxaminebetainecardiovascular diseasecholinecholine intakecognitionDHAGLP-1metabolic healthneurodevelopmentNuSHTMAO

Identifiers

PMID41305668
PMCPMC12655052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.