Evidence map›Paper›PMID 41305596›Full record

ReviewNutrients2025

Nutritional Approach in Pediatric Patients with Inflammatory Bowel Disease: Treatment, Risk and Challenges.

Maria Elena Capra, Arianna Maria Bellani, Martina Berzieri, Anna Giuseppina Montani, Tullia Sguerso, Valentina Aliverti, Gianlorenzo Pisseri, Susanna Esposito, Giacomo Biasucci

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maria Elena CapraPediatrics and Neonatology Unit, Guglielmo da Saliceto Hospital, 29121 Piacenza, Italy.ORCID 0000-0003-0848-5228
Arianna Maria BellaniPediatric Clinic, Azienda Ospedaliero-Universitaria, 43126 Parma, Italy.
Martina BerzieriPediatric Clinic, Azienda Ospedaliero-Universitaria, 43126 Parma, Italy.
Anna Giuseppina MontaniPediatric Clinic, Azienda Ospedaliero-Universitaria, 43126 Parma, Italy.
Tullia SguersoPediatric Clinic, Azienda Ospedaliero-Universitaria, 43126 Parma, Italy.
Valentina AlivertiPediatric Clinic, Azienda Ospedaliero-Universitaria, 43126 Parma, Italy.
Gianlorenzo PisseriPediatric Clinic, Azienda Ospedaliero-Universitaria, 43126 Parma, Italy.
Susanna EspositoPediatric Clinic, Azienda Ospedaliero-Universitaria, 43126 Parma, Italy.ORCID 0000-0003-4103-2837
Giacomo BiasucciPediatrics and Neonatology Unit, Guglielmo da Saliceto Hospital, 29121 Piacenza, Italy.ORCID 0000-0002-7441-9248

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory Bowel Diseases (IBDs), including Crohn's disease (CD) and ulcerative colitis (UC), have become a growing global health concern in children and adolescents. Pediatric-onset IBD presents unique challenges compared with adult-onset forms, including more extensive disease, impaired growth, delayed puberty, and psychosocial difficulties. While biologic and targeted therapies have advanced disease control, nutritional interventions remain a central component of management. Exclusive enteral nutrition (EEN) is recognized as the first-line therapy for inducing remission in pediatric CD, offering comparable efficacy to corticosteroids with additional benefits for mucosal healing, nutritional status, and growth. Modified dietary approaches, such as partial enteral nutrition and the Crohn's Disease Exclusion Diet (CDED), show promise for improving adherence and maintaining remission. However, dietary restrictions may lead to deficiencies and psychosocial stress, underscoring the importance of individualized, dietitian-supervised care. The role of nutrition in UC is less defined, but balanced, anti-inflammatory dietary patterns appear beneficial. This narrative review summarizes current evidence on nutritional strategies in pediatric IBD, highlighting their therapeutic potential, limitations, and integration with pharmacologic treatment within a multidisciplinary framework aimed at optimizing outcomes and quality of life.

Indexed as

Colitis, UlcerativeCrohn DiseaseEnteral NutritionInflammatory Bowel DiseasesAdolescentChildHumansNutritional StatusNutrition TherapyQuality of LifeadolescentschildrenCrohn’s diseasedietary interventionfuture perspectivesulcerative colitis

Identifiers

PMID41305596
PMCPMC12655807

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.