Fisetin Inhibits Periodontal Pathogen-Induced EMT in Oral Squamous Cell Carcinoma via the Wnt/β-Catenin Pathway.

Ruoyao Zhang, Hiroki Takigawa, Hugo Maruyama, Takayuki Nambu, Chiho Mashimo, Toshinori Okinaga

Abstract read

In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

A multi-omics integration of bulk and single-cell transcriptomics identifies and validates a 16-gene epithelial-mesenchymal transition prognostic signature in tongue squamous cell carcinoma.Translational cancer research · 2026
Article
Molecules (Basel, Switzerland) · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ruoyao ZhangGraduate School of Dentistry (Microbiology), Osaka Dental University, Hirakata 573-1121, Japan.

Hiroki TakigawaDepartment of Microbiology, Osaka Dental University, Hirakata 573-1121, Japan.

Hugo MaruyamaDepartment of Microbiology, Osaka Dental University, Hirakata 573-1121, Japan.ORCID 0000-0002-2190-7109

Takayuki NambuDepartment of Microbiology, Osaka Dental University, Hirakata 573-1121, Japan.ORCID 0000-0002-0474-1389

Chiho MashimoDepartment of Microbiology, Osaka Dental University, Hirakata 573-1121, Japan.

Toshinori OkinagaDepartment of Microbiology, Osaka Dental University, Hirakata 573-1121, Japan.ORCID 0000-0002-0598-5246

Funding

Japan Society for the Promotion of Science (JSPS) KAKENHI JP22K09954

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsEpithelial-Mesenchymal TransitionFlavonolsMouth NeoplasmsSquamous Cell Carcinoma of Head and NeckWnt Signaling Pathwaybeta CateninCadherinsCell Line, TumorCell MovementCell SurvivalCoculture TechniquesFusobacterium nucleatumHumansPorphyromonas gingivalisAntineoplastic Agentsbeta CateninCadherinsfisetinFlavonolsepithelial–mesenchymal transition (EMT)oral squamous cell carcinoma (OSCC)periodontal pathogensWnt/β-catenin

Identifiers

PMID41305575

DOI10.3390/nu17223522

PMCPMC12655663

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.