Evidence map›Paper›PMID 41305509›Full record

ArticleViruses2025

Multi-Omic Analysis of Bacteriophage-Insensitive Mutants Reveals a Putative Role for the Rcs Two-Component Phosphorelay System in Phage Resistance Development in

Nassereldin Ibrahim, Janet T Lin, Darlene Nesbitt, Joshua Tang, Dharamdeo Singh, Lawrence D Goodridge, Dion Lepp, Antonet M Svircev, Joel T Weadge, Hany Anany

Abstract read
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nassereldin IbrahimGuelph Research and Development Centre, Agriculture and Agri-Food Canada, Guelph, ON N1G 5C9, Canada.ORCID 0000-0003-0054-8394
Janet T LinGuelph Research and Development Centre, Agriculture and Agri-Food Canada, Guelph, ON N1G 5C9, Canada.
Darlene NesbittAgriculture and Agri-Food Canada, London Research and Development Centre, Vineland Station, ON L0R 2E0, Canada.
Joshua TangGuelph Research and Development Centre, Agriculture and Agri-Food Canada, Guelph, ON N1G 5C9, Canada.ORCID 0009-0005-2370-8364
Dharamdeo SinghFood Science Department, University of Guelph, Guelph, ON N1G 2W1, Canada.ORCID 0009-0005-7726-7912
Lawrence D GoodridgeFood Science Department, University of Guelph, Guelph, ON N1G 2W1, Canada.ORCID 0009-0008-9965-3509
Dion LeppGuelph Research and Development Centre, Agriculture and Agri-Food Canada, Guelph, ON N1G 5C9, Canada.ORCID 0000-0003-3740-4706
Antonet M SvircevAgriculture and Agri-Food Canada, London Research and Development Centre, Vineland Station, ON L0R 2E0, Canada.
Joel T WeadgeDepartment of Biology, Wilfrid Laurier University, Waterloo, ON N2L 3C5, Canada.ORCID 0000-0002-8020-0015
Hany AnanyGuelph Research and Development Centre, Agriculture and Agri-Food Canada, Guelph, ON N1G 5C9, Canada.

Funding

Agriculture and Agri-Food Canada J-001733, J-002861, J-002617Natural Sciences and Engineering Research Council of Canada 229971
6 · The paper itself

Abstract

Phage therapy has garnered significant attention due to the rise of life-threatening multidrug-resistant pathogenic bacteria and the growing awareness of the transfer of resistance genes between pathogens. Considering this, phage therapy applications are being extended to target plant pathogenic bacteria, such as

Indexed as

Bacterial ProteinsErwinia amylovoraBiofilmsMalusMutationMyoviridaePhage TherapyPodoviridaeBacterial Proteinsbacteriophage resistancebiopesticidefire blightlytic phagesphage-carrier system

Identifiers

PMID41305509
PMCPMC12656757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.