Evidence map›Paper›PMID 41305489›Full record

ArticleViruses2025

ORF3 Gene of Porcine Epidemic Diarrhea Virus Causes Nuclear and Morphological Distortions with Associated Cell Death.

Ndirangu A Kamau, Jae-Rang Rho, Eui-Soon Park, Jung-Eun Yu, Ji-Yun Yu, Gianmarco Ferrara, Hyun-Jin Shin

Abstract read
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ndirangu A KamauLaboratory of Infectious Diseases, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Republic of Korea.ORCID 0009-0008-0428-4473
Jae-Rang RhoDepartment of Microbiology & Molecular Biology, College of Bioscience & Biotechnology, Chungnam National University, 220 Gungdong, Yuseong, Daejeon 34134, Republic of Korea.ORCID 0000-0002-0019-4939
Eui-Soon ParkDepartment of Microbiology & Molecular Biology, College of Bioscience & Biotechnology, Chungnam National University, 220 Gungdong, Yuseong, Daejeon 34134, Republic of Korea.
Jung-Eun YuDepartment of Microbiology & Molecular Biology, College of Bioscience & Biotechnology, Chungnam National University, 220 Gungdong, Yuseong, Daejeon 34134, Republic of Korea.
Ji-Yun YuDepartment of Microbiology & Molecular Biology, College of Bioscience & Biotechnology, Chungnam National University, 220 Gungdong, Yuseong, Daejeon 34134, Republic of Korea.
Gianmarco FerraraDepartment of Veterinary Science, University of Messina, Polo Universitario dell'Annunziata, 98168 Messina, Italy.ORCID 0000-0001-5837-7976
Hyun-Jin ShinLaboratory of Infectious Diseases, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Republic of Korea.ORCID 0000-0002-6805-4924

Funding

National Research Foundation of Korea RS-2023-NR076878
6 · The paper itself

Abstract

There is increasing research interest in the ORF3 accessory protein of PEDV as a critical element for viral virulence. Here, wild type ORF3 (ORF3

Indexed as

Cell DeathCell NucleusCoronavirus InfectionsPorcine epidemic diarrhea virusViral ProteinsAnimalsChlorocebus aethiopsCytoplasmSwineSwine DiseasesVero CellsVirulenceViral ProteinsnuclearORF3PEDVtransmembranetruncated

Identifiers

PMID41305489
PMCPMC12656750

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.