Evidence map›Paper›PMID 41305482›Full record

ArticleViruses2025

Transcriptomics Reveals the Inhibitory Effect of Scutellarin on PRRSV-Infected PAMs.

Guidong Zhang, Teng Tu, Yanwei Li, Yueyan Zeng, Mingpeng Hu, Chengchao Du, Zexiao Yang, Xueping Yao, Dishi Chen, Tian Shi and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Guidong ZhangCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Teng TuDivision of Student Affairs, Chengdu University of Technology, Chengdu 610059, China.
Yanwei LiCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0009-0005-8355-036X
Yueyan ZengCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-5659-152X
Mingpeng HuCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Chengchao DuCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0009-0005-8239-4676
Zexiao YangCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Xueping YaoCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Dishi ChenSichuan Provincial Animal Disease Prevention and Control Center, Chengdu 610047, China.
Tian ShiChengdu Animal Disease Prevention and Control Center, Chengdu 610041, China.
Yin WangCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine reproductive and respiratory syndrome (PRRS) is a highly contagious epidemic caused by the porcine reproductive and respiratory syndrome virus (PRRSV). Characterized by reproductive disorders in pregnant sows and respiratory symptoms in pigs of all ages, it poses a severe threat to the global swine industry. In recent years, the high mutation rate of PRRSV has increasingly limited the effectiveness of vaccines against it, prompting the search for new anti-PRRSV drugs. scutellarin (SCU), a natural flavonoid compound extracted from the medicinal plant

Indexed as

Antiviral AgentsApigeninGlucuronatesMacrophages, AlveolarPorcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusTranscriptomeAnimalsCell LineGene Expression ProfilingSignal TransductionSwineVirus ReplicationAntiviral AgentsApigeninGlucuronatesscutellarinporcine reproductive and respiratory syndrome virusscutellarintranscriptomic analysis

Identifiers

PMID41305482
PMCPMC12656885

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.