Evidence map›Paper›PMID 41305390›Full record

Observational studyPathogens (Basel, Switzerland)2025

MDR Bacteremia in the Critically Ill During COVID-19: The MARTINI Study.

Karolina Akinosoglou, Christina Petropoulou, Vasiliki Karioti, Sotiria Kefala, Dimitrios Bousis, Vasiliki Stamouli, Fevronia Kolonitsiou, George Dimopoulos, Charalambos Gogos, Foteini Fligou

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Karolina AkinosoglouDepartment of Medicine, University of Patras, 26504 Patras, Greece.ORCID 0000-0002-4289-9494
Christina PetropoulouDepartment of Medicine, University of Patras, 26504 Patras, Greece.
Vasiliki KariotiDepartment of Tourism Management, University of Patras, 26504 Patras, Greece.
Sotiria KefalaDepartment of Medicine, University of Patras, 26504 Patras, Greece.
Dimitrios BousisIntensive Care Unit, University General Hospital of Patras, 26504 Patras, Greece.ORCID 0000-0002-1972-096X
Vasiliki StamouliDepartment of Microbiology, University General Hospital of Patras, 26504 Patras, Greece.
Fevronia KolonitsiouDepartment of Medicine, University of Patras, 26504 Patras, Greece.ORCID 0000-0002-4348-6077
George Dimopoulos3rd Department of Critical Care, Evgenidio Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0002-3784-3103
Charalambos GogosDepartment of Medicine, University of Patras, 26504 Patras, Greece.
Foteini FligouDepartment of Medicine, University of Patras, 26504 Patras, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multidrug-resistant (MDR) bloodstream infections (BSIs) constitute a major challenge in intensive care units, with the COVID-19 pandemic compromising infection control and potentially increasing MDR incidence. Comparative data between COVID and non-COVID ICU populations remain limited. The MARTINI study is a retrospective observational analysis held in a tertiary hospital during the COVID-19 pandemic (2020-2022) encompassing adult patients with MDR BSIs admitted to COVID and non-COVID ICUs. Demographics, comorbidities, severity scores, microbiology, resistance patterns, and outcomes were accessed and compared. A binary logistic regression model and multivariate regression was performed to identify independent predictors of ICU mortality. Among the study's 156 patients (106 COVID-ICU, 50 non-COVID-ICU), COVID-ICU patients were significantly older with higher comorbidity and severity scores. Gram-negative pathogens predominated in both cohorts, mainly

Indexed as

BacteremiaCOVID-19Drug Resistance, Multiple, BacterialAgedAnti-Bacterial AgentsCritical IllnessFemaleHospital MortalityHumansIntensive Care UnitsMaleMiddle AgedRetrospective StudiesSARS-CoV-2Anti-Bacterial Agentsantimicrobial resistanceCOVID-ICUcritically illmultidrug resistant pathogensnon-COVID ICUSARS-CoV-2

Identifiers

PMID41305390
PMCPMC12655241

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.