Evidence map›Paper›PMID 41305347›Full record

ArticlePathogens (Basel, Switzerland)2025

Dalbavancin for Bone and Joint Infections: A Two-Center Greek Real-World Retrospective Study.

Christina Petropoulou, Petros Ioannou, Georgios Eleftherakis, Stefania Papazisi, Christos Davoulos, Eugenia Drosou, Anastasia Spiliopoulou, Ekaterini Tsiata, Fotini Paliogianni, Diamantis Kofteridis and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Christina PetropoulouDepartment of Internal Medicine, University Hospital of Patras, 26504 Patras, Greece.
Petros IoannouDepartment of Internal Medicine, University Hospital of Heraklion, 71110 Heraklion, Greece.ORCID 0000-0003-1082-5674
Georgios EleftherakisDepartment of Internal Medicine, University Hospital of Patras, 26504 Patras, Greece.
Stefania PapazisiDepartment of Internal Medicine, University Hospital of Heraklion, 71110 Heraklion, Greece.
Christos DavoulosDepartment of Internal Medicine, University Hospital of Patras, 26504 Patras, Greece.
Eugenia DrosouDepartment of Internal Medicine, University Hospital of Patras, 26504 Patras, Greece.
Anastasia SpiliopoulouDepartment of Microbiology, University Hospital of Patras, 26504 Patras, Greece.ORCID 0000-0001-9125-8098
Ekaterini TsiataDepartment of Pharmacy, University Hospital of Patras, 26504 Patras, Greece.
Fotini PaliogianniDepartment of Microbiology, University Hospital of Patras, 26504 Patras, Greece.
Diamantis KofteridisDepartment of Internal Medicine, University Hospital of Heraklion, 71110 Heraklion, Greece.ORCID 0000-0003-0255-5926
Markos MarangosDepartment of Internal Medicine, University Hospital of Patras, 26504 Patras, Greece.ORCID 0000-0001-5030-2398
Stelios F AssimakopoulosDepartment of Internal Medicine, University Hospital of Patras, 26504 Patras, Greece.ORCID 0000-0002-6901-3681

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone and joint infections remain therapeutic challenges, usually requiring prolonged intravenous therapy and hospitalization. Dalbavancin, a long-acting lipoglycopeptide, offers a simplified alternative. We retrospectively analysed 83 patients treated with dalbavancin for osteomyelitis, spondylodiscitis, septic arthritis, or prosthetic joint infection in two tertiary Greek hospitals (2022-2024). Mean age was 69 ± 16 years; 56.6% were male; Charlson Comorbidity Index averaged 4 ± 2.25. Common comorbidities included diabetes (28.9%) and coronary artery disease (18.1%). Infections were vertebral osteomyelitis/spondylodiscitis (48.2%), non-vertebral osteomyelitis (38.5%), prosthetic joint infection (10.8%), and septic arthritis (8.4%). Microbiological diagnosis was established in 62.6%; predominant pathogens were

Indexed as

Anti-Bacterial AgentsArthritis, InfectiousOsteomyelitisTeicoplaninAgedAged, 80 and overDiscitisFemaleGreeceHumansMaleMiddle AgedProsthesis-Related InfectionsRetrospective StudiesTreatment OutcomeAnti-Bacterial AgentsdalbavancinTeicoplanindalbavancinGram-positive bacteriaosteomyelitisprosthetic joint infectionseptic arthritisspondylodiscitis

Identifiers

PMID41305347
PMCPMC12655752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.