Evidence map›Paper›PMID 41305343›Full record

ArticlePathogens (Basel, Switzerland)2025

Trem2-MICAL1-P-ERK Axis in Macrophages Confers Protection Against

Xiaoyu Geng, Haochen Yang, Zihan Wang, Ziqian Chen, Jinling Chen, Mei Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaoyu GengDepartment of Pathogen Biology, School of Medicine, Nantong University, Nantong 226001, China.ORCID 0009-0002-4195-6861
Haochen YangDepartment of Pathogen Biology, School of Medicine, Nantong University, Nantong 226001, China.
Zihan WangDepartment of Pathogen Biology, School of Medicine, Nantong University, Nantong 226001, China.
Ziqian ChenDepartment of Pathogen Biology, School of Medicine, Nantong University, Nantong 226001, China.
Jinling ChenDepartment of Pathogen Biology, School of Medicine, Nantong University, Nantong 226001, China.
Mei YangResearch Center of Clinical Medicine, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China.

Funding

National Natural Science Foundation of China 81401683Natural Science Foundation of Jiangsu Province BK20251836Natural Science Foundation of Nantong Municipality JC2023100Natural Science Foundation of Nantong Municipality JC2024029
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MacrophagesMembrane GlycoproteinsPregnancy Complications, ParasiticReceptors, ImmunologicToxoplasmaToxoplasmosisAnimalsDisease Models, AnimalFemaleHumansMAP Kinase Signaling SystemMiceMice, Inbred C57BLPregnancyPregnancy OutcomeSignal TransductionMembrane GlycoproteinsReceptors, ImmunologicTrem2 protein, mouseplacental immunitysoluble T. gondii antigensToxoplasma gondiiTrem2

Identifiers

PMID41305343
PMCPMC12655669

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.