Evidence map›Paper›PMID 41305316›Full record

ArticlePathogens (Basel, Switzerland)2025

The Impact of Body Mass Index on Latent Tuberculosis Infection: Combined Assessment in People Living with HIV.

Jingxian Ning, Peng Lu, Yuchen Pan, Yilin Lian, Yu Zhang, Wenxin Jiang, Leonardo Martinez, Limei Zhu, Qiao Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jingxian NingDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Peng LuDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.ORCID 0000-0003-2703-7578
Yuchen PanDepartment of Chronic Communicable Disease, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
Yilin LianDepartment of Chronic Communicable Disease, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
Yu ZhangDepartment of Chronic Communicable Disease, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
Wenxin JiangDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Leonardo MartinezDepartment of Epidemiology, School of Public Health, Boston University, Boston, MA 02118, USA.
Limei ZhuDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Qiao LiuDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.

Funding

National Nature Science Foundation of China 82574173, 82003516
6 · The paper itself

Abstract

backgroundTuberculosis (TB) is a leading cause of death among people living with HIV (PLHIV). While body mass index (BMI) affects TB risk, its association with latent tuberculosis infection (LTBI) in PLHIV is unclear. High-transmission settings, such as prisons, may further increase LTBI risk, yet this relationship has not been studied across both prison and community populations of PLHIV.

methodsWe conducted a dual cross-sectional study of PLHIV in Jiangsu Province, China, recruiting participants from a prison hospital in 2021 and community healthcare facilities from July to November 2023. BMI was calculated from measured height and weight. LTBI was identified by a positive ESAT6-CFP10 (EC) skin test or the QuantiFERON-TB Gold In-Tube (QFT-GIT) assay. Logistic regression and generalized additive models (GAMs) assessed the association between BMI and LTBI, adjusting for demographic, clinical, and behavioral confounders.

resultsA total of 1799 PLHIV were included in the analysis, of whom 343 (19.07%) were recruited from prison settings and 1456 (80.93%) from community-based screening. The overall prevalence of LTBI was 13.79% (

conclusionIn summary, obesity is significantly associated with a lower risk of LTBI among PLHIV, with an approximate 54% risk reduction. This inverse relationship was most pronounced when using the EC skin test.

Indexed as

Body Mass IndexHIV InfectionsLatent TuberculosisAdultChinaCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceRisk Factorsbody mass indexESAT6-CFP10 skin testlatent tuberculosis infectionpeople living with HIV

Identifiers

PMID41305316
PMCPMC12655615

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.