Antibacterial Electrophoretically Loaded Titania Nanotubes on Titanium Alloy Implants Enhance Osseointegration.

Julia Fischer, Deborah J Hall, Meghan M Moran, Adrienn Markovics, Peter H Pennekamp, John L Hamilton, Markus A Wimmer

Abstract read

In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Chitosan and Chitin-Derived Biomaterials in Orthopedics: A Structured Narrative Review of Polymer Design, Quantitative Performance, and Clinical Translation.Polymers · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julia FischerTribology Laboratory, Department of Orthopedics, Rush University Medical Center, Chicago, IL 60612, USA.

Deborah J HallImplant Pathology Laboratory, Department of Orthopedics, Rush University Medical Center, Chicago, IL 60607, USA.ORCID 0000-0002-7121-7261

Meghan M MoranDepartment Anatomy & Cell Biology, Rush University Medical Center, Chicago, IL 60607, USA.ORCID 0000-0001-7801-4849

Adrienn MarkovicsDivision of Rheumatology, Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA.

Peter H PennekampKlinik fuer Orthopaedie und Unfallchirurgie, Alterstraumatologie, Cellitinen-Krankenhaus St. Hildegardis, 50931 Koeln, Germany.

John L HamiltonTribology Laboratory, Department of Orthopedics, Rush University Medical Center, Chicago, IL 60612, USA.ORCID 0000-0002-0716-9816

Markus A WimmerTribology Laboratory, Department of Orthopedics, Rush University Medical Center, Chicago, IL 60612, USA.ORCID 0000-0001-6169-3873

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary hip and knee arthroplasties are common surgeries in the U.S., with periprosthetic joint infection (PJI) being the leading cause of implant revision. Systemic antibiotics often fail to achieve sufficient local concentrations, driving interest in localized drug delivery. Titanium (Ti) implants modified with titania nanotubes (TNTs) provide an increased surface area for drug loading and controlled release. Previous studies have shown that gentamicin-loaded TNTs inhibit

Indexed as

Anti-Bacterial AgentsNanotubesOsseointegrationProstheses and ImplantsTitaniumAlloysAnimalsChitosanCoated Materials, BiocompatibleGentamicinsMiceMice, Inbred C57BLStaphylococcus aureusAlloysAnti-Bacterial AgentsChitosanCoated Materials, BiocompatibleGentamicinsTitaniumtitanium alloy (TiAl6V4)titanium dioxideanimal testantibacterial coatingchitosanelectrophoretic loadinggentamicinmouse femur implantosseointegrationpull-out testtitania nanotubes

Identifiers

PMID41305310

DOI10.3390/pathogens14111072

PMCPMC12655275

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.