ArticlePharmaceuticals (Basel, Switzerland)2025
Design, Synthesis, and Biological Evaluation of 5',7-Disubstituted 7-Deaza-adenosine Analogues as Irreversible Pan-FGFR Inhibitors.
Jung Hoon Park, Phuong Thao Tran, Hye Lin Ko, Seonghee Mun, Sung Chul Jang, Dong Hyun Moon, Jaeho Han, Jieun Kim, Gibae Kim, Hongseok Choi and 6 more
Abstract read
In one paragraphArticle in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
16 authors.
Jung Hoon ParkRepublic of Korea Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Phuong Thao TranRepublic of Korea Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0009-0005-5207-1403 Hye Lin KoRepublic of Korea Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0009-0009-2962-6078 Seonghee MunRepublic of Korea Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0009-0005-6926-3196 Sung Chul JangRepublic of Korea Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Dong Hyun MoonRepublic of Korea Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Jaeho HanRepublic of Korea Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Jieun KimRepublic of Korea Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0009-0006-4905-9355 Gibae KimRepublic of Korea Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0002-9930-712X Hongseok ChoiRepublic of Korea Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0009-0008-0394-1523 Seung Woo KimRepublic of Korea Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Minjae KimRepublic of Korea Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Sang Kook LeeRepublic of Korea Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0002-4306-7024 Byung Woo HanRepublic of Korea Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0001-7571-3791 Keon Wook KangRepublic of Korea Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Lak Shin JeongRepublic of Korea Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0002-3441-707X Funding
Ministry of Health and Welfare HI23C0721National Research Foundation of Korea NRF-2021R1A2B02001544National Research Foundation of Korea NRF-2022R1A6A1A03046247
6 · The paper itselfAbstract
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Indexed as
covalent inhibitorsmetabolic stabilitymolecular dynamics simulationsnucleoside analoguespan-FGFR inhibitorsX-ray crystallography
Identifiers
PMID41304987
PMCPMC12655421
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