Evidence map›Paper›PMID 41304863›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

An Investigational Study on the Role of ADME Agents' Genetic Variation on DD217 Pharmacokinetics and Safety Profile.

Dmitry A Sychev, Sherzod P Abdullaev, Anastasia V Rudik, Alexander V Dmitriev, Svetlana N Tuchkova, Natalia P Denisenko, Denis S Makarov, Karin B Mirzaev

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dmitry A SychevFederal State Budgetary Research Institution «Russian Research Center of Surgery Named After Academician B.V. Petrovsky», Abrikosovsky Lane, 2, 119991 Moscow, Russia.ORCID 0000-0002-4496-3680
Sherzod P AbdullaevFederal State Budgetary Research Institution «Russian Research Center of Surgery Named After Academician B.V. Petrovsky», Abrikosovsky Lane, 2, 119991 Moscow, Russia.ORCID 0000-0001-9001-1499
Anastasia V RudikInstitute of Biomedical Chemistry, Bldg. 8, 10, Pogodinskaya Str., 119121 Moscow, Russia.ORCID 0000-0002-8916-9675
Alexander V DmitrievInstitute of Biomedical Chemistry, Bldg. 8, 10, Pogodinskaya Str., 119121 Moscow, Russia.ORCID 0000-0002-2431-3429
Svetlana N TuchkovaFederal State Budgetary Research Institution «Russian Research Center of Surgery Named After Academician B.V. Petrovsky», Abrikosovsky Lane, 2, 119991 Moscow, Russia.ORCID 0009-0001-2744-2752
Natalia P DenisenkoFederal State Budgetary Research Institution «Russian Research Center of Surgery Named After Academician B.V. Petrovsky», Abrikosovsky Lane, 2, 119991 Moscow, Russia.ORCID 0000-0003-3278-5941
Denis S MakarovAvexima Diol LLC, 690922 Vladivostok, Russia.
Karin B MirzaevFederal State Budgetary Research Institution «Russian Research Center of Surgery Named After Academician B.V. Petrovsky», Abrikosovsky Lane, 2, 119991 Moscow, Russia.

Funding

Federal Scientific-technical program for genetic technologies development for 2019-2030 075-15-2025-463Russian Science Foundation 25-25-00148
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ABCB1 (P-glycoprotein)DD217Dimolegindirect oral anticoagulantsgeneticsin silicopharmacogeneticspharmacokinetics

Identifiers

PMID41304863
PMCPMC12655527

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.