Correlations Between Rheology, In Situ Mucosal Retention and In Vivo Immunogenicity Reveal the Potential and Limitations of Mucoadhesive Excipients for Sublingual Vaccine Delivery.

Mohamed Deifallah Yousif, Ilona Kubajewska, Fatme Mawas, Sudaxshina Murdan

Abstract read

In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohamed Deifallah YousifUCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK.ORCID 0000-0003-2180-0480

Ilona KubajewskaUCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK.ORCID 0000-0002-6751-4722

Fatme MawasVaccines Division, Scientific Research & Innovation Group, MHRA, Potters Bar EN6 3QG, UK.

Sudaxshina MurdanUCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK.ORCID 0000-0003-0834-7757

Funding

BactiVac, the Bacterial Vaccines Network (funded through the GCRF Networks in Vaccines Re-search and Development, which was co-funded by the UKRI MRC and BBSRC), and The De-partment of Health and Social Care as part of the Global AMR Innovation Fund (GAMR N/A

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

chitosan (MGC)correlationsexcipientshydroxypropyl methylcellulose (HPMC)immunogenicitymucoadhesivemucosal immunitypolymerssublingual deliveryvaccine

Identifiers

PMID41304795

DOI10.3390/pharmaceutics17111456

PMCPMC12655090

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.