Evidence map›Paper›PMID 41304731›Full record

ArticlePharmaceutics2025

Transcriptional and Post-Transcriptional Anticholestatic Mechanisms of Obeticholic Acid in Lipopolysaccharide-Induced Cholestasis.

María Valeria Razori, Geraldine L Hillotte, Pamela L Martín, Ismael R Barosso, Cecilia L Basiglio, María Laura Ruiz, Marcelo G Roma

Abstract read
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

María Valeria RazoriInstitute of Experimental Physiology (IFISE), Department of Physiological Sciences, Faculty of Biochemical and Pharmaceutical Sciences, National University of Rosario, Rosario 2000, Argentina.
Geraldine L HillotteInstitute of Experimental Physiology (IFISE), Department of Physiological Sciences, Faculty of Biochemical and Pharmaceutical Sciences, National University of Rosario, Rosario 2000, Argentina.
Pamela L MartínInstitute of Experimental Physiology (IFISE), Department of Physiological Sciences, Faculty of Biochemical and Pharmaceutical Sciences, National University of Rosario, Rosario 2000, Argentina.ORCID 0000-0001-9051-6294
Ismael R BarossoInstitute of Experimental Physiology (IFISE), Department of Physiological Sciences, Faculty of Biochemical and Pharmaceutical Sciences, National University of Rosario, Rosario 2000, Argentina.ORCID 0000-0001-7400-8118
Cecilia L BasiglioInstitute of Experimental Physiology (IFISE), Department of Physiological Sciences, Faculty of Biochemical and Pharmaceutical Sciences, National University of Rosario, Rosario 2000, Argentina.
María Laura RuizInstitute of Experimental Physiology (IFISE), Department of Physiological Sciences, Faculty of Biochemical and Pharmaceutical Sciences, National University of Rosario, Rosario 2000, Argentina.ORCID 0000-0003-3693-5679
Marcelo G RomaInstitute of Experimental Physiology (IFISE), Department of Physiological Sciences, Faculty of Biochemical and Pharmaceutical Sciences, National University of Rosario, Rosario 2000, Argentina.ORCID 0000-0002-1660-9801

Funding

Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación PICT 2019-1965Consejo Nacional de Investigaciones Científicas y Técnicas PIP 2022-2024-11220210100552COIntercept Pharmaceuticals (United States) Investigator-Initiated Study ITT-15030
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

bile saltsBsephepatocellular transporterslipopolysaccharide-induced cholestasismultidrug resistance-associated protein 2obeticholic acid

Identifiers

PMID41304731
PMCPMC12655158

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.