Evidence map›Paper›PMID 41304500›Full record

ArticleToxics2025

From Safety Evaluation to Influencing Factors Analysis: A Comprehensive Investigation on Ocular Irritation of Baby Bath Products.

Qidi He, Yurong Zhong, Peining Li, Yanhua Guo, Chengkai Mei, Dongmei Xu, Erping Yan, Shaofeng Xi, Guoshan He, Jianhua Tan

Abstract read
In one paragraph

Article in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Qidi HeGuangzhou Quality Testing and Inspection Institute, National Quality Supervision and Testing Center for Cosmetics (Guangzhou), Guangzhou 510000, China.ORCID 0009-0007-4109-7645
Yurong ZhongKangaroo Mommy Research Centre, Guangdong Kangaroo Mommy Biotechnology Co., Ltd., Guangzhou 510000, China.
Peining LiGuangzhou Quality Testing and Inspection Institute, National Quality Supervision and Testing Center for Cosmetics (Guangzhou), Guangzhou 510000, China.
Yanhua GuoGuangzhou Quality Testing and Inspection Institute, National Quality Supervision and Testing Center for Cosmetics (Guangzhou), Guangzhou 510000, China.
Chengkai MeiGuangzhou Quality Testing and Inspection Institute, National Quality Supervision and Testing Center for Cosmetics (Guangzhou), Guangzhou 510000, China.
Dongmei XuKangaroo Mommy Research Centre, Guangdong Kangaroo Mommy Biotechnology Co., Ltd., Guangzhou 510000, China.
Erping YanKangaroo Mommy Research Centre, Guangdong Kangaroo Mommy Biotechnology Co., Ltd., Guangzhou 510000, China.
Shaofeng XiGuangzhou Quality Testing and Inspection Institute, National Quality Supervision and Testing Center for Cosmetics (Guangzhou), Guangzhou 510000, China.
Guoshan HeGuangzhou Quality Testing and Inspection Institute, National Quality Supervision and Testing Center for Cosmetics (Guangzhou), Guangzhou 510000, China.
Jianhua TanGuangzhou Quality Testing and Inspection Institute, National Quality Supervision and Testing Center for Cosmetics (Guangzhou), Guangzhou 510000, China.

Funding

Guangdong Administration for Market Regulation science and technology project 2024CZ22Guangdong Administration for Market Regulation science and technology project 2025CZ05Guangzhou Science and technology planning project 2023B04J0407State Administration for Market Regulation science and technology project 2023MK144
6 · The paper itself

Abstract

Given the underdevelopment and sensitivity of babies' eyes, frequently used baby bath products have garnered attention for their ocular irritation safety. The selection and application of raw materials are key factors. We tested 39 commercial baby bath products for ocular irritation safety and proposed a novel evaluation method using the "Risk Attention Index" to analyze formulation risk factors. The ocular irritation potential of 39 commonly used raw materials under typical usage conditions was investigated via animal and cell models. Results showed over 20% of commercial products had safety risks. Surfactants like cocamidopropyl betaine (CAPB), sodium laureth sulfate (SLES), and sodium lauroamphoacetate (SLA) had the highest "Risk Attention Index", requiring special attention. Some fragrance components were also potential irritants. Combining SLES with panthenol, maltooligosyl glucoside/hydrogenated starch hydrolysate, and Tween

Indexed as

baby bath productscombinationocular irritationsodium laureth sulfatesurfactantstypical usage concentration

Identifiers

PMID41304500
PMCPMC12656482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.