ArticlePolymers2025
Preparation and Paclitaxel-Loading of Regenerated Chitin Nanoparticles.
Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
This study aims to investigate biodegradable and biocompatible chitin as a natural carrier for loading the hydrophobic anti-cancer drug paclitaxel (PTX) for the first time, resulting in a new loading system of chitin nanoparticles-paclitaxel (ChNps-PTX). The well-dispersed chitin nanoparticles (ChNps) and ChNps-PTX were prepared via a water-dripping regeneration method. The functional groups, crystal form, and the high degree of acetylation (DA = 96.03%) of ChNps did not change during regeneration, suggesting that ChNps retained the complete molecular structure of chitin. The average particle size of ChNps-PTX was approximately 93.11 nm, which was larger than that of ChNps (84.06 nm) because of loading PTX (the drug loading was approximately 8.01%). TEM and CLSM were employed to confirm PTX existence in ChNps-PTX, and the nano-strip PTX (30.52 ± 6.78 nm in length and 16.02 ± 2.77 nm in width) was found for the first time. Loading of PTX resulted in ChNps-PTX presenting a new characteristic peak at 1734 cm
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.