Evidence map›Paper›PMID 41304375›Full record

ReviewPolymers2025

Therapeutic Applications of 3D Bioprinting in Surgery for Female Reproductive Tract Disorders: A Systematic Review.

Joaquín Gómez-Abellán, Raquel López-Flores, Juan A Sánchez-Margallo, Soledad Sánchez-Mateos, Francisco M Sánchez-Margallo

Abstract readReview
In one paragraph

Review in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joaquín Gómez-AbellánBioengineering and Health Technologies Unit, Jesús Usón Minimally Invasive Surgery Centre, 10071 Cáceres, Spain.ORCID 0009-0003-5070-8429
Raquel López-FloresAssisted Reproduction Unit, Jesús Usón Minimally Invasive Surgery Centre, 10071 Cáceres, Spain.ORCID 0009-0005-0688-9626
Juan A Sánchez-MargalloBioengineering and Health Technologies Unit, Jesús Usón Minimally Invasive Surgery Centre, 10071 Cáceres, Spain.ORCID 0000-0002-0100-2695
Soledad Sánchez-MateosAssisted Reproduction Unit, Jesús Usón Minimally Invasive Surgery Centre, 10071 Cáceres, Spain.ORCID 0000-0002-7545-1485
Francisco M Sánchez-MargalloRed RICORS-TERAV, ISCIII, 28222 Madrid, Spain.ORCID 0000-0003-2138-988X

Funding

This work has been financed by the Ministry of Science and Innovation with funds from the European Union Next Generation EU, from the Recovery, Transformation and Resilience Plan (PRTR-C17.I1) and the European Regional Development Fund (ERDF) of Extremadu PRTR-C17.I1
6 · The paper itself

Abstract

Three-dimensional printing has been progressively integrated into various industries, particularly the medical sector, where its significance in tissue engineering for transplantation is growing exponentially. The purpose of this systematic review is to ascertain whether the bioprinting of scaffolds holds the potential to provide treatment for pathologies within the female reproductive system. The inclusion criteria applied were the bioimprinting of the ovary, uterus, endometrium, or vagina, intended for surgical implantation in the patient. Articles employing printing methods that do not incorporate cells embedded in the material, those that generate tissue other than that of the female reproductive system, and those that print structures with in vitro applications were excluded from the review. The search for relevant articles was conducted until 3 April 2025. After analyzing 667 articles extracted from PubMed, Scopus and Web of Science, 13 articles were included in this review. The analysis of the results encompassed aspects related to the bioprinting technology employed, the hydrogels and cells utilized, as well as the bioprinted structure and the corresponding target tissue. Few studies investigated the creation of a multicellular scaffold and in none of the cases was it implanted in a large animal model, only in murine and rabbit models. These articles reaffirm the feasibility of employing 3D bioprinting to fabricate tissues and functional organs in the present and future. This advancement will revolutionize the future demand for organs for transplantation.

Indexed as

3D bioprintingassisted reproductionfemaleregenerative medicinetissue engineering

Identifiers

PMID41304375
PMCPMC12656174

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.