Evidence map›Paper›PMID 41303526›Full record

ArticleInternational journal of molecular sciences2025

COL10A1 Overexpression Promotes Gastric Cancer Aggressiveness Through EMT and Major Oncogenic Pathways.

Laura G Necula, Denisa L Dragu, Lilia Matei, Ioana Pitica, Simona O Dima, Coralia Bleotu, Carmen C Diaconu, Mihaela Chivu-Economescu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Laura G NeculaCellular and Molecular Pathology Department, Stefan S. Nicolau Institute of Virology, 030304 Bucharest, Romania.
Denisa L DraguCellular and Molecular Pathology Department, Stefan S. Nicolau Institute of Virology, 030304 Bucharest, Romania.ORCID 0000-0002-5868-2636
Lilia MateiCellular and Molecular Pathology Department, Stefan S. Nicolau Institute of Virology, 030304 Bucharest, Romania.ORCID 0000-0003-4479-655X
Ioana PiticaCellular and Molecular Pathology Department, Stefan S. Nicolau Institute of Virology, 030304 Bucharest, Romania.ORCID 0000-0001-7440-9798
Simona O DimaCenter of Excellence in Translational Medicine, Fundeni Clinical Institute, 020021 Bucharest, Romania.ORCID 0000-0001-5275-8938
Coralia BleotuCellular and Molecular Pathology Department, Stefan S. Nicolau Institute of Virology, 030304 Bucharest, Romania.ORCID 0000-0002-9031-338X
Carmen C DiaconuCellular and Molecular Pathology Department, Stefan S. Nicolau Institute of Virology, 030304 Bucharest, Romania.
Mihaela Chivu-EconomescuDepartment of Strategy, Education, Documentation, and IT (SEDI), Stefan S. Nicolau Institute of Virology, 030304 Bucharest, Romania.ORCID 0000-0001-7512-4700

Funding

EU's NextGenerationEU instrument through the National Recovery and Resilience Plan of Ro-mania - Pillar III-C9-I, section I5. Establishment and operationalization of Competence Centers PNRR-III-C9-2022 - I5, managed by the Ministry of Research, Innovation 760009/30.12.2022, code CF 14/16.11.2022Romanian Academy Research program of the Romanian Academy 2025
6 · The paper itself

Abstract

Gastric cancer (GC) remains a major cause of cancer-related mortality, with limited options for early detection and precision therapy. Collagen family members are increasingly recognized as key structural and regulatory components of the tumor microenvironment.

Indexed as

Collagen Type XEpithelial-Mesenchymal TransitionStomach NeoplasmsApoptosisCarcinogenesisCell Line, TumorCell MovementCell ProliferationGene Expression Regulation, NeoplasticHumansNeoplasm InvasivenessSignal TransductionCOL10A1 protein, humanCollagen Type XCOL10A1collagengastric cancertumor microenvironment

Identifiers

PMID41303526
PMCPMC12652929

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.