Copper(II) Complexes of Selected Acylhydrazones as Potential Biological Agents.

Izabela Czyżewska, Liliana Mazur, Robert Mroczka, Anna Biernasiuk, Anna Hordyjewska, Łukasz Popiołek

Abstract read

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Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Izabela CzyżewskaChair and Department of Organic Chemistry, Faculty of Pharmacy, Medical University of Lublin, 4A Chodźki Street, 20-093 Lublin, Poland.

Liliana MazurInstitute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Skłodowska University, Maria Curie-Skłodowska Sq. 2, 20-031 Lublin, Poland.ORCID 0000-0001-8283-3484

Robert MroczkaLaboratory of X-ray Optics, Centre for Interdisciplinary Research, The John Paul II Catholic University of Lublin, 1J Konstantynów Street, 20-708 Lublin, Poland.

Anna BiernasiukChair and Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Medical University of Lublin, 1 Chodźki Street, 20-093 Lublin, Poland.ORCID 0000-0002-2844-9876

Anna HordyjewskaDepartment of Medicinal Chemistry, Faculty of Medical Sciences, Medical University of Lublin, 4A Chodźki Street, 20-093 Lublin, Poland.ORCID 0000-0003-3104-8464

Łukasz PopiołekChair and Department of Organic Chemistry, Faculty of Pharmacy, Medical University of Lublin, 4A Chodźki Street, 20-093 Lublin, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the current research a series of new copper(II) complexes with novel acylhydrazone ligands were synthesized and their antibacterial and anticancer activities were determined. The complexes were characterized by molecular spectroscopy (FT-IR and UV-Vis) and conductivity measurements. Additionally, their structure was confirmed by single-crystal X-ray analysis. The crystallographic data revealed that all compounds are mononuclear Cu(II) species. The Cu(II) ion is four-coordinated by the ONO donor set from mono-deprotonated hydrazone ligand and one Cl

Indexed as

Anti-Bacterial AgentsAntineoplastic AgentsCoordination ComplexesCopperHydrazonesCell Line, TumorHumansLigandsMicrococcus luteusStaphylococcus epidermidisAnti-Bacterial AgentsAntineoplastic AgentsCoordination ComplexesCopperHydrazonesLigandsacylhydrazonesantibacterial activityanticancer activitycopper(II) complexescrystal structurecytotoxicityhalogen bond

Identifiers

PMID41303463

DOI10.3390/ijms262210980

PMCPMC12652143

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.