Evidence map›Paper›PMID 41303462›Full record

ArticleInternational journal of molecular sciences2025

SOX9, GATA3, and GATA4 Overexpression in Liposarcomas: Insights into the Molecular Biology of Adipocytic Sarcomas.

Andrei-Ionuț Patrichi, Zsolt Kovács, Ioan Jung, Simona Gurzu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrei-Ionuț PatrichiDepartment of Pathology, George Emil Palade University of Medicine, Pharmacy, Science and Technology, 540139 Targu-Mures, Romania.
Zsolt KovácsDepartment of Biochemistry, George Emil Palade University of Medicine, Pharmacy, Science and Technology, 540139 Targu-Mures, Romania.
Ioan JungDepartment of Pathology, George Emil Palade University of Medicine, Pharmacy, Science and Technology, 540139 Targu-Mures, Romania.
Simona GurzuDepartment of Pathology, George Emil Palade University of Medicine, Pharmacy, Science and Technology, 540139 Targu-Mures, Romania.ORCID 0000-0003-3968-5118

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liposarcomas represent a heterogeneous group of malignant mesenchymal neoplasms, with diverse histological subtypes and molecular alterations. This study aimed to investigate the gene expression profiles of SOX9, GATA3, and GATA4 in liposarcoma subtypes and to assess their associations with clinicopathological parameters. Forty-two formalin-fixed, paraffin-embedded liposarcoma samples were analyzed. Total RNA was extracted, reverse-transcribed, and quantified by qRT-PCR using GAPDH as an endogenous control. Relative quantification (RQ) values were categorized, and statistical analyses included Fisher's exact test, Kaplan-Meier survival analysis, and Cox proportional hazards modeling. SOX9 expression significantly varied among histological subtypes (

Indexed as

GATA3 Transcription FactorGATA4 Transcription FactorLiposarcomaSOX9 Transcription FactorAdultAgedBiomarkers, TumorFemaleGene Expression Regulation, NeoplasticHumansKaplan-Meier EstimateMaleMiddle AgedPrognosisBiomarkers, TumorGATA3 protein, humanGATA3 Transcription FactorGATA4 protein, humanGATA4 Transcription FactorSOX9 protein, humanSOX9 Transcription FactorGATA3GATA4gene expressionliposarcomaSOX9

Identifiers

PMID41303462
PMCPMC12652793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.