Evidence map›Paper›PMID 41303447›Full record

ReviewInternational journal of molecular sciences2025

Left Ventricular Remodeling After Myocardial Infarction-Pathophysiology, Diagnostic Approach and Management During Cardiac Rehabilitation.

Víctor Marcos-Garcés, Carlos Bertolín-Boronat, Héctor Merenciano-González, María Luz Martínez Mas, Josefa Inés Climent Alberola, Laura López-Bueno, Alfonso Payá Rubio, Nerea Pérez-Solé, César Ríos-Navarro, Elena de Dios and 6 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Journal of thoracic disease · 2026
    Article
  2. Review
  3. Article
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  7. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Víctor Marcos-GarcésDepartment of Cardiology, Hospital Clinico Universitario de Valencia, 46010 Valencia, Spain.ORCID 0000-0001-5565-5547
Carlos Bertolín-BoronatDepartment of Cardiology, Hospital Clinico Universitario de Valencia, 46010 Valencia, Spain.ORCID 0000-0002-4751-5859
Héctor Merenciano-GonzálezDepartment of Cardiology, Hospital Clinico Universitario de Valencia, 46010 Valencia, Spain.ORCID 0000-0002-1734-0381
María Luz Martínez MasDepartment of Cardiology, Hospital Clinico Universitario de Valencia, 46010 Valencia, Spain.
Josefa Inés Climent AlberolaDepartment of Rehabilitation, Hospital Clinico Universitario de Valencia, 46010 Valencia, Spain.
Laura López-BuenoDepartment of Rehabilitation, Hospital Clinico Universitario de Valencia, 46010 Valencia, Spain.ORCID 0000-0002-4024-0418
Alfonso Payá RubioDepartment of Rehabilitation, Hospital Clinico Universitario de Valencia, 46010 Valencia, Spain.ORCID 0000-0002-8009-809X
Nerea Pérez-SoléINCLIVA Health Research Institute, 46010 Valencia, Spain.ORCID 0000-0003-3527-0337
César Ríos-NavarroINCLIVA Health Research Institute, 46010 Valencia, Spain.ORCID 0000-0002-6405-6279
Elena de DiosNetwork Biomedical Research Center for Cardiovascular Diseases (CIBER-CV), 28029 Madrid, Spain.
Jose GavaraINCLIVA Health Research Institute, 46010 Valencia, Spain.ORCID 0000-0002-3483-7066
David MoratalNetwork Biomedical Research Center for Cardiovascular Diseases (CIBER-CV), 28029 Madrid, Spain.ORCID 0000-0002-2825-3646
Jose F Rodriguez-PalomaresNetwork Biomedical Research Center for Cardiovascular Diseases (CIBER-CV), 28029 Madrid, Spain.ORCID 0000-0002-7229-9780
Jose T Ortiz-PérezInstitut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.ORCID 0000-0001-8043-6055
Juan SanchisDepartment of Cardiology, Hospital Clinico Universitario de Valencia, 46010 Valencia, Spain.ORCID 0000-0003-0797-8709
Vicente BodiDepartment of Cardiology, Hospital Clinico Universitario de Valencia, 46010 Valencia, Spain.

Funding

Conselleria d'Educació, Universitats i Ocupació AEST/2019/037 and AEST/2020/029Conselleria d'Educació, Universitats i Ocupació CIAPOS/2023/247Conselleria d'Educació, Universitats i Ocupació CIPROM/2024/028Conselleria de Innovación, Universidades, Ciencia y Sociedad Digital CIGE/2022/26Instituto de Salud Carlos III CB16/11/00420Instituto de Salud Carlos III CB16/11/00479Instituto de Salud Carlos III CB16/11/00486Instituto de Salud Carlos III CM21/00175Instituto de Salud Carlos III CM23/00246Instituto de Salud Carlos III JR23/00032Instituto de Salud Carlos III PI23/01150
6 · The paper itself

Abstract

Despite the improvement in prognosis in patients with acute myocardial infarction (AMI), a significant proportion of survivors still experience heart failure (HF)-related adverse outcomes. Adverse left ventricular remodeling (LVR), which refers to a progressive dilation of left ventricular (LV) end-diastolic and end-systolic volumes, usually accompanied by a deterioration in LV systolic function, occurs frequently and underlies most cases of HF development after AMI. In this review, we discuss the current definitions of post-AMI LVR, the most appropriate imaging modalities for its detection, and the pathophysiological mechanisms by which Cardiac Rehabilitation (CR) can improve LVR-including exercise interventions, cardiovascular risk factors control, and pharmacological therapy optimization. Finally, we provide up-to-date recommendations for the follow-up and management of LVR in post-AMI patients enrolled in CR and outline future prospects on this topic.

Indexed as

Cardiac RehabilitationMyocardial InfarctionVentricular RemodelingHeart FailureHumanscardiac magnetic resonancecardiac rehabilitationechocardiographyexercise trainingleft ventricular remodelingmyocardial infarction

Identifiers

PMID41303447
PMCPMC12652362

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.