ReviewInternational journal of molecular sciences2025
Advance in Managing Indoor Cat Allergen Proteins: Molecular Insights, Detection, and Control.
Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Human Allergy to Cats and Dogs: Molecular and Environmental Determinants, Diagnosis, and Precision Management.Veterinary sciences · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Indoor cat allergens, particularly the major allergen Fel d 1 protein, represent significant environmental triggers for allergic rhinitis, asthma, and other immune-related disorders in humans. With the continuous global increase in pet ownership, cat allergen proteins are prevalent in diverse settings and can even be transmitted to pet-free locations via clothing and animal fur, thereby posing health risks to sensitized individuals. This review systematically summarizes the molecular characteristics, distribution patterns, and mechanisms of human sensitization to indoor cat allergen proteins. It focuses on a comparative analysis of the principles, sensitivity, and application of commonly used immunological methods (such as various modified ELISAs, immunoblotting, and high-throughput multiplex detection technologies) alongside emerging real-time sensing platforms (including QCM, SAW, and LIF). Furthermore, this review summarizes key factors affecting indoor allergen concentrations, such as cat characteristics, architectural environments, human activities, and spatiotemporal variations. It also evaluates the efficacy and limitations of current allergy control strategies, covering source control (e.g., gene editing, immunomodulation), environmental management (e.g., air filtration), and medical treatments (e.g., allergen immunotherapy), and discusses future prospects. This review aims to offer a scientific foundation and systematic reference for the detection, control, and public health protection related to indoor cat allergens.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.