Modular Flow Synthesis of Citric Acid-Coated Superparamagnetic Iron Oxide Nanoparticles: Preliminary Results.

Sabina Vohl, Andreja Nemet, Janja Stergar

Abstract read

In one paragraph

Article in Micromachines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sabina VohlFaculty of Chemistry and Chemical Engineering, University of Maribor, Smetanova 17, SI-2000 Maribor, Slovenia.

Andreja NemetFaculty of Chemistry and Chemical Engineering, University of Maribor, Smetanova 17, SI-2000 Maribor, Slovenia.

Janja StergarFaculty of Chemistry and Chemical Engineering, University of Maribor, Smetanova 17, SI-2000 Maribor, Slovenia.ORCID 0000-0003-3317-2573

Funding

Slovenian Research and Innovation Agency (ARIS) P2-0006, P2-0414, J2-60044

6 · The paper itself

Abstract

Superparamagnetic iron oxide nanoparticles (SPIONs) with sizes below 10 nm are biocompatible and non-toxic, making them promising for biomedical applications. To prevent their agglomeration and enhance their functionality, the nanoparticles were coated with citric acid (CA), which modifies the surface charge, improves dispersion stability, and facilitates biomedical use. In this work, a modular flow-through microreactor system was employed to synthesize and coat the nanoparticles in a single, continuous two-step process. The system enables precise control over temperature and mixing, ensuring uniform reaction conditions and minimizing hot spots. The synthesized Fe

Indexed as

citric acidcontinuous synthesismodular flow microreactor systemsuperparamagnetic iron oxide nanoparticleszeta potential measurements

Identifiers

PMID41302746

DOI10.3390/mi16111228

PMCPMC12654078

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.