Evidence map›Paper›PMID 41302558›Full record

ArticleInternational journal of environmental research and public health2025

Deprescribing Central Nervous System-Active Medications Among Community-Dwelling Older Adults with Dementia in Primary Care: A Feasibility Study.

Elizabeth A Phelan, Benjamin H Balderson, Monica M Fujii, Vina F Graham, Mary Kay Theis, Shelly L Gray

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elizabeth A PhelanDepartment of Medicine, Division of Gerontology and Geriatric Medicine, School of Medicine, University of Washington, Seattle, WA 98104, USA.ORCID 0009-0009-3047-1237
Benjamin H BaldersonKaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, WA 98101, USA.ORCID 0000-0002-7370-9016
Monica M FujiiKaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, WA 98101, USA.
Vina F GrahamKaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, WA 98101, USA.
Mary Kay TheisKaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, WA 98101, USA.
Shelly L GrayDepartment of Pharmacy, School of Pharmacy, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0001-5507-1859

Funding

Training Core (I)U54AG063546 · NIA · BROWN UNIVERSITY · PI JASON H KARLAWISH · 2019 to 2026
$125.9M
NIA NIH HHS U54AG063546
6 · The paper itself

Abstract

Central nervous system (CNS)-active medications pose serious health risks for older adults with dementia but are nonetheless commonly used. Few deprescribing interventions have focused on people with dementia. We conducted a one-arm pilot study in six primary care practices of an integrated healthcare system between February and August 2023. The deprescribing intervention consisted of patient/care partner education and self-management materials and provider decision support. Participants were aged 60+ with diagnosed dementia and prescribed at least one CNS-active medication for three or more months of the six-month period prior to study start. We assessed feasibility and acceptability of the intervention and feasibility of ascertaining medication discontinuation and medically treated falls. The intervention was delivered to all (

Indexed as

Central Nervous System AgentsDementiaDeprescriptionsAgedAged, 80 and overFeasibility StudiesFemaleHumansIndependent LivingMaleMiddle AgedPilot ProjectsPrimary Health CareCentral Nervous System Agentsageddementiadeprescriptionsfallspotentially inappropriate medication listprimary health care

Identifiers

PMID41302558
PMCPMC12652246

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.