Evidence map›Paper›PMID 41302399›Full record

ArticleMolecules (Basel, Switzerland)2025

Bioactivity-Directed Isolation of Anticancer Constituents from Underexplored Folklore:

Saira Tabassum, Joham Sarfraz Ali, Rida Fatima Saeed, Madiha Asghar, Myra Akhtar, Abdul Momin Rizwan Ahmad, Muhammad Zia

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Saira TabassumNational Center for Bioinformatics, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Joham Sarfraz AliDepartment of Biological Sciences, National University of Medical Sciences (NUMS), Rawalpindi 46000, Pakistan.
Rida Fatima SaeedDepartment of Biological Sciences, National University of Medical Sciences (NUMS), Rawalpindi 46000, Pakistan.ORCID 0000-0003-1577-1062
Madiha AsgharNational Center for Bioinformatics, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Myra AkhtarDepartment of Biological Sciences, International Islamic University, Islamabad 45500, Pakistan.
Abdul Momin Rizwan AhmadDepartment of Human Nutrition and Dietetics, NUST School of Health Sciences, National University of Sciences & Technology (NUST), Sector H-12, Islamabad 44000, Pakistan.ORCID 0000-0003-3499-902X
Muhammad ZiaNational Center for Bioinformatics, Quaid-i-Azam University, Islamabad 45320, Pakistan.ORCID 0000-0002-4878-6810

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedicinal plants continue to offer a promising source of novel bioactive compounds for cancer therapy due to their affordability, biocompatibility, and low toxicity.

methodsThis study employed a bioactivity-guided isolation strategy to identify and characterize anticancer constituents from

resultsComparative analysis of spectral data (UV, 1D/2D NMR, and ESI-MS) led to the identification of three triterpenoid compounds-Lupeol, Cycloartenol, and β-sitosterol-reported for the first time from

conclusionThe findings validate the ethnopharmacological use of

Indexed as

Antineoplastic AgentsAntineoplastic Agents, PhytogenicPlant ExtractsRhusAnimalsAntioxidantsArtemiaCell Line, TumorHumansMedicine, TraditionalPhytochemicalsPlant LeavesAntineoplastic AgentsAntineoplastic Agents, PhytogenicAntioxidantsPhytochemicalsPlant Extractsantioxidant assaysbioactive compoundsbioassay guided isolationcytotoxicity assaysin vivomedicinal plantNF-κB

Identifiers

PMID41302399
PMCPMC12655016

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.