ArticleLife (Basel, Switzerland)2025
Histological Analysis of Multiple Unilateral Testicular Tumors in Dogs.
Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Transcriptomic Profiling of Canine Testicular Leydig Cell Tumors Uncovers Key Upregulated Gene Pathways.Animals : an open access journal from MDPI · 2026Article
- Comprehensive Insight into the Male Dog Reproductive System in Health and Diseases: Developmental, Genetic, and Environmental Factors-Review on Research and Clinical Trials.Veterinary sciences · 2026Review
- Clinical Management of Testicular Tumors in Dogs.Animals : an open access journal from MDPI · 2026Review
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Testicular tumors are, after skin tumors, the most common neoplasms in male dogs. Among all animals, these tumors occur most frequently within dogs. The etiology remains unclear, although the ectopic (non-scrotal) positioning of the testicles has an influence on tumor development. The most common types of testicular tumors include seminomas, Sertoli cell tumors, and interstitial (Leydig) cell tumors. The aim of this study was a retrospective evaluation of preserved material. A total of 326 cases of testicular tumors in dogs, diagnosed between 2017 and 2024, were analyzed. A histological analysis of multiple unilateral testicular tumors was conducted, and the frequency of occurrence was determined. 27 instances (8.28%) of multiple tumors within the same testicle were identified. The most recurrent combination was seminoma and interstitial cell tumors-12 cases (44.44%), followed by Sertoli cell and Leydig cell tumors-6 cases (22.22%), and seminoma and Sertoli cell tumors-6 cases (22.22%). In three cases, the presence of three tumors within a single testicle was observed (11.11%). In one case, double tumors were found within both testicles. It was observed that malignant features, as in cases of single testicular tumors, are rare.
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