Evidence map›Paper›PMID 41302186›Full record

ArticleLife (Basel, Switzerland)2025

Preoperative Risk Factors and Phenotypic Clustering in Periprosthetic Joint Infection: A Matched Case-Control Study.

Tarek Omar Pacha, Sophia K Klett, Gabi von Lewinski, Maximilian Koblenzer, Hür Özbek, Jorge Mayor, Jan D Clausen, Axel Gänsslen, Schayan Faraj Tabrizi, Stephan Sehmisch and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tarek Omar PachaDepartment of Trauma and Orthopaedic Surgery, Hannover Medical School (Medizinische Hochschule Hannover), Carl-Neuberg-Straße 1, 30625 Hannover, Lower Saxony, Germany.
Sophia K KlettDepartment of Trauma and Orthopaedic Surgery, Hannover Medical School (Medizinische Hochschule Hannover), Carl-Neuberg-Straße 1, 30625 Hannover, Lower Saxony, Germany.
Gabi von LewinskiDepartment of Trauma and Orthopaedic Surgery, Hannover Medical School (Medizinische Hochschule Hannover), Carl-Neuberg-Straße 1, 30625 Hannover, Lower Saxony, Germany.
Maximilian KoblenzerDepartment of Trauma and Orthopaedic Surgery, Hannover Medical School (Medizinische Hochschule Hannover), Carl-Neuberg-Straße 1, 30625 Hannover, Lower Saxony, Germany.
Hür ÖzbekDepartment of Trauma and Orthopaedic Surgery, Hannover Medical School (Medizinische Hochschule Hannover), Carl-Neuberg-Straße 1, 30625 Hannover, Lower Saxony, Germany.
Jorge MayorDepartment of Trauma and Orthopaedic Surgery, Hannover Medical School (Medizinische Hochschule Hannover), Carl-Neuberg-Straße 1, 30625 Hannover, Lower Saxony, Germany.
Jan D ClausenDepartment of Trauma and Orthopaedic Surgery, Hannover Medical School (Medizinische Hochschule Hannover), Carl-Neuberg-Straße 1, 30625 Hannover, Lower Saxony, Germany.
Axel GänsslenDepartment of Trauma and Orthopaedic Surgery, Hannover Medical School (Medizinische Hochschule Hannover), Carl-Neuberg-Straße 1, 30625 Hannover, Lower Saxony, Germany.
Schayan Faraj TabriziDepartment of Trauma and Orthopaedic Surgery, Hannover Medical School (Medizinische Hochschule Hannover), Carl-Neuberg-Straße 1, 30625 Hannover, Lower Saxony, Germany.
Stephan SehmischDepartment of Trauma and Orthopaedic Surgery, Hannover Medical School (Medizinische Hochschule Hannover), Carl-Neuberg-Straße 1, 30625 Hannover, Lower Saxony, Germany.
Gökmen F AktasDepartment of Trauma and Orthopaedic Surgery, Hannover Medical School (Medizinische Hochschule Hannover), Carl-Neuberg-Straße 1, 30625 Hannover, Lower Saxony, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periprosthetic joint infection (PJI) remains one of the most serious complications after total joint arthroplasty. This retrospective 1:1 matched case-control study investigated preoperative predictors and patient phenotypes associated with PJI in 182 patients (91 cases, 91 controls) undergoing hip or knee arthroplasty between 2013 and 2024. Variables with skewed distributions were log-transformed, and multivariable logistic regression with LASSO regularization identified independent risk factors. Unsupervised K-means clustering was applied to perioperative features to explore data-driven patient phenotypes. Preoperative anemia (OR 5.91,

Indexed as

machine learning in orthopedicsperiprosthetic joint infection (PJI)phenotypic clusteringpreoperative risk factorsrisk stratificationtotal joint arthroplasty

Identifiers

PMID41302186
PMCPMC12654038

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.