Evidence map›Paper›PMID 41302166›Full record

ArticleLife (Basel, Switzerland)2025

Disparities in Colorectal Cancer Mortality and Survival Trends Among Hispanics Living in Puerto Rico (2000-2021): A Comparison Between Early-Onset and Average-Onset Disease.

Camille Montalvo-Pacheco, Carlos R Torres-Cintrón, Marilyn Moró-Carrión, Hilmaris Centeno-Girona, Luis D Borrero-García, María González-Pons

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Camille Montalvo-PachecoDivision of Clinical and Translational Cancer Research, University of Puerto Rico Comprehensive Cancer Center, San Juan 00921, Puerto Rico.
Carlos R Torres-CintrónPuerto Rico Central Cancer Registry, San Juan 00921, Puerto Rico.ORCID 0000-0002-3614-7034
Marilyn Moró-CarriónDivision of Clinical and Translational Cancer Research, University of Puerto Rico Comprehensive Cancer Center, San Juan 00921, Puerto Rico.
Hilmaris Centeno-GironaDivision of Clinical and Translational Cancer Research, University of Puerto Rico Comprehensive Cancer Center, San Juan 00921, Puerto Rico.ORCID 0000-0002-2271-4560
Luis D Borrero-GarcíaDivision of Clinical and Translational Cancer Research, University of Puerto Rico Comprehensive Cancer Center, San Juan 00921, Puerto Rico.ORCID 0000-0002-5256-7581
María González-PonsDivision of Clinical and Translational Cancer Research, University of Puerto Rico Comprehensive Cancer Center, San Juan 00921, Puerto Rico.ORCID 0000-0002-3694-0534

Funding

Social determinants of health associated to the cervical cancer-related care across the cancer control continuum among women living with HIV in Puerto RicoP20GM148324 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI Vivian Colon · 2023 to 2026
$10.3M
Cancer Prevention and Control (CAPAC) Research Training ProgramR25CA240120 · NCI · COMPREHENSIVE CANCER CENTER/ UNIV/PR · PI ANA Patricia ORTIZ, Marievelisse Soto-Salgado · 2019 to 2026
$2.8M
Cancer Prevention and Control (CAPAC) Research Training Program R25CA240120Center for the Promotion of Cancer Health Equity P20GM148324NCI NIH HHS R25 CA240120NIGMS NIH HHS P20 GM148324Puerto Rico Central Cancer Registry NU58DP007164
6 · The paper itself

Abstract

Colorectal cancer (CRC) is the leading cause of cancer-related death in Puerto Rico, a U.S. territory with noted disparities in CRC incidence, particularly among those with early-onset disease (EOCRC). Although EOCRC incidence has been consistently increasing in the U.S. mainland, and a disparate burden has been reported among Hispanics, EOCRC mortality and survival are yet to be assessed among Hispanics living in Puerto Rico (PRH). In this study, we analyzed EOCRC mortality and survival trends in PRH and compared these to those of other U.S. populations. Mortality data were obtained from the Puerto Rico Central Cancer Registry and the Surveillance, Epidemiology, and End Results (SEER) program. Descriptive characteristics and temporal trends were derived via SEER*Stat software (version 9.0.42) and Joinpoint regression models, respectively. Relative survival was estimated using the Actuarial method and the Ederer II approach. Overall, CRC mortality trends showed a decline, but an increase in EOCRC mortality among Hispanics. PRH exhibited the lowest 5-year survival in regional cancers (54.10%), with NHB having the lowest survival among younger individuals. This study highlights significant disparities in EOCRC mortality trends and underscores an urgent need for targeted public health strategies and research efforts to address the disproportionate burden of EOCRC among PRH.

Indexed as

colorectal cancer mortalitycolorectal cancer survivaldisparitiesearly-onset colorectal cancerHispanicracial and ethnic

Identifiers

PMID41302166
PMCPMC12653479

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.