Evidence map›Paper›PMID 41302068›Full record

ArticleLife (Basel, Switzerland)2025

Advancing Duodenoscope Reprocessing with Alginate-Coated Calcium Peroxide Nanoparticles.

Adrian Fifere, Cristian-Dragos Varganici, Elena-Laura Ursu, Tudor Pinteala, Vasile Sandru, Ioana-Andreea Turin-Moleavin, Irina Rosca, Gheorghe G Balan

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adrian FiferePetru Poni Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley 41A, 700487 Iasi, Romania.
Cristian-Dragos VarganiciPetru Poni Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley 41A, 700487 Iasi, Romania.ORCID 0000-0002-4813-9162
Elena-Laura UrsuPetru Poni Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley 41A, 700487 Iasi, Romania.ORCID 0000-0002-3699-7311
Tudor PintealaPetru Poni Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley 41A, 700487 Iasi, Romania.ORCID 0000-0001-7664-0918
Vasile SandruDepartment of Gastroenterology, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0001-6206-6126
Ioana-Andreea Turin-MoleavinPetru Poni Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley 41A, 700487 Iasi, Romania.
Irina RoscaPetru Poni Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley 41A, 700487 Iasi, Romania.ORCID 0000-0003-3080-1709
Gheorghe G BalanFaculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-2919-4940

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesAlthough significant advances in duodenoscope reprocessing have been introduced since mid-2010s-including enhanced cleaning protocols, disposable distal endcaps, and the introduction of fully single-use duodenoscopes-residual contamination and infection risks remain unresolved. Moreover, repeated reprocessing may cause cumulative damage to the polymer surfaces, elevator mechanisms, and internal channels of the duodenoscopes, making them more susceptible to residual contamination. To minimize the duodenoscope polymer degradation caused by intensive use and reprocessing, new alternatives are urgently needed. In this context, calcium peroxide nanoparticles coated with sodium alginate (CaO

methodsThe disinfectant properties of the CaO

resultsThe nanoparticles exhibited important antimicrobial activity against the reference bacterial strains

conclusionsThe CaO

Indexed as

alginateantibacterialcalcium peroxide nanoparticlesdisinfectantduodenoscope reprocessing

Identifiers

PMID41302068
PMCPMC12653724

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.