Evidence map›Paper›PMID 41301776›Full record

ReviewBiomedicines2025

From Biomechanics to Bioinnovation: Emerging Applications of Piezoelectric Materials and Phenomena in Dentistry.

Wen Kang, Yuehui Wang, Dan Zhao, Hongwei Wang, Sijing Xie, Lijia Pan

Abstract readReview
In one paragraph

Review in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wen KangNanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing 210008, China.ORCID 0000-0001-6095-9879
Yuehui WangCollaborative Innovation Center of Advanced Microstructures, School of Electronic Science and Engineering, Nanjing University, Nanjing 210093, China.ORCID 0009-0009-8049-6766
Dan ZhaoNanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing 210008, China.ORCID 0000-0002-5306-9840
Hongwei WangState Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing 210093, China.ORCID 0000-0003-2868-5112
Sijing XieNanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing 210008, China.
Lijia PanCollaborative Innovation Center of Advanced Microstructures, School of Electronic Science and Engineering, Nanjing University, Nanjing 210093, China.ORCID 0000-0002-8917-7843

Funding

Guangdong Provincial R&D Program in Key Areas 2023B0101200011National Key Research and Development Program of China 2021YFA1401100 and 2022YFF0710801National Natural Science Foundation of China 61825403, 61921005 and 82370899
6 · The paper itself

Abstract

Teeth are the hardest organs in the human body. As mineralized structures, they possess a unique microstructure composed of orderly arranged piezoelectric materials such as hydroxyapatite crystals and collagen fibers. Teeth exhibit effective piezoelectric coefficients of approximately 1.2-1.6 pC/N. This inherent property enables teeth to function as natural piezoelectric sensors, converting routine mechanical stresses (e.g., chewing and biting forces, typically ranging from 22.4 to 68.3 kg) into localized electrical signals. This characteristic is of great importance in dentistry and materials science, offering new perspectives into a deeper understanding of the physiological functions and pathological mechanisms of teeth. Despite promising advances, challenges regarding the clinical translation, long-term stability, and biosafety of piezoelectric materials in the oral environment remain unresolved. This review highlights the biological functions of the piezoelectric properties of teeth, discusses recent applications and notable advancements of piezoelectric materials in dentistry, and outlines the challenges and research priorities for future clinical applications.

Indexed as

dentistrypiezoelectric biomaterialspiezoelectricityteeth

Identifiers

PMID41301776
PMCPMC12650311

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.