Evidence map›Paper›PMID 41301611›Full record

ArticleAntibiotics (Basel, Switzerland)2025

Repurposing MK-8245 as a Quorum Sensing Inhibitor to Suppress Virulence and Potentiate Antibiotic Activity in

Giulia Bernabè, Giovanni Marzaro, Mahmoud Elsayed Mosaad Shalata, Daniela Iosob, Valentina Inglima, Massimo Bellato, Ignazio Castagliuolo, Paola Brun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giulia BernabèDepartment of Molecular Medicine, University of Padua, 35121 Padua, Italy.ORCID 0000-0001-5564-7010
Giovanni MarzaroDepartment of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy.
Mahmoud Elsayed Mosaad ShalataDepartment of Molecular Medicine, University of Padua, 35121 Padua, Italy.ORCID 0009-0005-3594-2561
Daniela IosobDepartment of Molecular Medicine, University of Padua, 35121 Padua, Italy.
Valentina InglimaDepartment of Molecular Medicine, University of Padua, 35121 Padua, Italy.
Massimo BellatoDepartment of Information Engineering, University of Padua, 35131 Padua, Italy.ORCID 0000-0001-7428-0656
Ignazio CastagliuoloDepartment of Molecular Medicine, University of Padua, 35121 Padua, Italy.
Paola BrunDepartment of Molecular Medicine, University of Padua, 35121 Padua, Italy.ORCID 0000-0002-3279-9000

Funding

Cariparo Excellence Project "Restoring Antibiotic sensitivity in Bacteria: A synthetic biology ap-proach (ReActing)" 59576
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antimicrobial resistancebiofilmmolecular dockingquorum sensing inhibitorsvirulence

Identifiers

PMID41301611
PMCPMC12649364

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.