Evidence map›Paper›PMID 41301533›Full record

ReviewBiomolecules2025

Amylase Binding to Oral Streptococci: A Key Interaction for Human Oral Microbial Ecology, Adaptation and Fitness.

Amarpreet Sabharwal, Elaine M Haase, Frank A Scannapieco

Abstract readReview
In one paragraph

Review in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Host interactomes ofMicrobiology spectrum · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Amarpreet SabharwalSchulich School of Medicine and Dentistry, Western University, London, ON N6A 5C1, Canada.ORCID 0000-0002-9444-837X
Elaine M HaaseDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, Buffalo, NY 14214, USA.ORCID 0000-0002-8169-0319
Frank A ScannapiecoDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, Buffalo, NY 14214, USA.

Funding

NIH HHS 1C06DC022673-18NIH HHS 1R01DE022673-01
6 · The paper itself

Abstract

The interaction between human salivary alpha-amylase (HSAmy) and amylase-binding oral streptococci (ABS) helps determine the bacteria that colonize the oral cavity by establishing dental biofilms. Streptococci are important pioneer species of the oral cavity and influence oral health as well as common diseases such as dental caries. Various oral streptococcal species express distinct amylase-binding proteins, among which amylase-binding protein A (AbpA), encoded by the

Indexed as

AmylasesMouthStreptococcusAdaptation, PhysiologicalBacterial AdhesionBiofilmsHumansMicrobiotaAmylasesbacterial colonizationbiofilmdental plaquemicrobial evolutionsaliva

Identifiers

PMID41301533
PMCPMC12650345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.