ArticleBiomolecules2025
Ecological History Shapes Transcriptome Variation in Quiescent
Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Nuclear Dynamics in Quiescent Cells: Conserved Mechanisms from Yeasts to Mammals.Biomolecules · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Quiescence is a pivotal state for all living organisms and cells. However, recent research indicates a lack of uniformity among quiescent cells. That is, even if the primary feature of quiescence-the ability to restart divisions-is maintained, quiescent cells within populations exhibit variation in their cellular architecture and characteristics. While it is known that the process of entry into quiescence is influenced by a combination of nutrient starvation and temporal factors, the underlying mechanisms remain to be fully elucidated. In this study, we compare the transcriptomes of known homogenous fractions of dense quiescent yeast isolated from populations of different ecological histories. These populations have undergone experimental enrichment of certain types of quiescent cells during cycles of growth and starvation for 300 generations. Transcriptome analysis revealed discrepancies in terms of characteristics associated mainly with energy turnover processes, biosynthesis, and cell wall maintenance. The results of this study suggest that quiescent cells possess the capacity to adapt their transcriptome activity in accordance with their evolutionary history.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.