Evidence map›Paper›PMID 41301127›Full record

ArticleBioengineering (Basel, Switzerland)2025

Development of a Machine Learning Model for Predicting Treatment-Related Amenorrhea in Young Women with Breast Cancer.

Long Song, Zobaida Edib, Uwe Aickelin, Hadi Akbarzadeh Khorshidi, Anne-Sophie Hamy, Yasmin Jayasinghe, Martha Hickey, Richard A Anderson, Matteo Lambertini, Margherita Condorelli and 27 more

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Long SongSchool of Computing and Information Systems, The University of Melbourne, Parkville, VIC 3052, Australia.ORCID 0000-0001-8494-4364
Zobaida EdibDepartment of Obstetrics, Gynaecology and Newborn Health, Faculty of Medicine, Dentistry & Health Sciences, The University of Melbourne, Parkville, VIC 3052, Australia.
Uwe AickelinSchool of Computing and Information Systems, The University of Melbourne, Parkville, VIC 3052, Australia.ORCID 0000-0002-2679-2275
Hadi Akbarzadeh KhorshidiSchool of Computing and Information Systems, The University of Melbourne, Parkville, VIC 3052, Australia.ORCID 0000-0002-2653-4102
Anne-Sophie HamyDepartment of Medical Oncology, Institut Curie, 26 rue d'Ulm, 75005 Paris, France.ORCID 0000-0003-4430-3022
Yasmin JayasingheDepartment of Obstetrics, Gynaecology and Newborn Health, Faculty of Medicine, Dentistry & Health Sciences, The University of Melbourne, Parkville, VIC 3052, Australia.ORCID 0000-0001-5975-9378
Martha HickeyDepartment of Obstetrics, Gynaecology and Newborn Health, Faculty of Medicine, Dentistry & Health Sciences, The University of Melbourne, Parkville, VIC 3052, Australia.
Richard A AndersonCentre for Reproductive Health, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh EH16 4UU, UK.
Matteo LambertiniDepartment of Medical Oncology, U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.ORCID 0000-0003-1797-5296
Margherita CondorelliResearch Laboratory on Human Reproduction, Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.
Isabelle DemeestereFertility Clinic, CUB-Hôpital Erasme, 1070 Brussels, Belgium.
Michail IgnatiadisInstitute Jules Bordet, 1070 Brussels, Belgium.
Barbara PistilliUNICANCER Federation, 75013 Paris, France.
H Irene SuDepartment of Obstetrics, Gynecology and Reproductive Sciences and Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-6671-5151
Shanton ChangSchool of Computing and Information Systems, The University of Melbourne, Parkville, VIC 3052, Australia.
Patrick Cheong-Iao PangFaculty of Applied Sciences, Macao Polytechnic University, Macao SAR, China.ORCID 0000-0002-8820-5443
Fabien ReyalDepartment of Breast and Gynecological Surgery, Institut Curie, 26 rue d'Ulm, 75005 Paris, France.
Scott M NelsonSchool of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow G31 2ER, UK.
Paniti SukumvanichDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Alessandro MinisiniDepartment of Oncology, University Hospital, Azienda Sanitaria Universitaria Friuli Centrale Udine, 33100 Udine, Italy.
Fabio PuglisiDepartment of Oncology, University Hospital, Azienda Sanitaria Universitaria Friuli Centrale Udine, 33100 Udine, Italy.
Kathryn J RuddyMayo Clinic, Phoenix, AZ 85054, USA.ORCID 0000-0001-6298-332X
Fergus J CouchMayo Clinic, Phoenix, AZ 85054, USA.
Janet E OlsonMayo Clinic, Phoenix, AZ 85054, USA.
Kate SternMelbourne IVF, East Melbourne, VIC 3002, Australia.
Franca AgrestaMelbourne IVF, East Melbourne, VIC 3002, Australia.
Lesley StaffordDepartment of Surgery, Faculty of Medicine, Dentistry & Health Sciences, The University of Melbourne, Parkville, VIC 3052, Australia.
Laura Chin-LennDepartment of Surgery, The Royal Melbourne Hospital, Parkville, VIC 3050, Australia.
Wanda CuiDepartment of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.
Antoinette AnazodoSydney Children's Hospital, Randwick, NSW 2031, Australia.ORCID 0000-0002-5495-6062
Alexandra GorelikMusculoskeletal Health and Wiser Health Care, School of Public Health and Preventive Medicine, Monash University, Clayton, VIC 3168, Australia.
Tuong L NguyenMelbourne School of Population and Global Health, Faculty of Medicine, Dentistry & Health Sciences, The University of Melbourne, Parkville, VIC 3052, Australia.ORCID 0000-0002-6597-8363
Ann PartridgeDana-Farber Cancer Institute, Boston, MA 02215, USA.
Christobel SaundersDepartment of Surgery, The Royal Melbourne Hospital, Parkville, VIC 3050, Australia.
Elizabeth SullivanCollege of Health, Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW 2308, Australia.
Mary Macheras-MagiasBreast Cancer Network Australia, Camberwell, VIC 3124, Australia.
Michelle PeateDepartment of Obstetrics, Gynaecology and Newborn Health, Faculty of Medicine, Dentistry & Health Sciences, The University of Melbourne, Parkville, VIC 3052, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment-induced ovarian function loss is a significant concern for many young patients with breast cancer. Accurately predicting this risk is crucial for counselling young patients and informing their fertility-related decision-making. However, current risk prediction models for treatment-related ovarian function loss have limitations. To provide a broader representation of patient cohorts and improve feature selection, we combined retrospective data from six datasets within the FoRECAsT (In

Indexed as

breast cancercross imputationmachine learningrisk prediction modeltreatment-related amenorrhea

Identifiers

PMID41301127
PMCPMC12649454

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.