Evidence map›Paper›PMID 41301082›Full record

ReviewCancers2025

Lacrimal Sac Tumors: A Histotype-Driven Literature Review.

Luca Giovanni Locatello, Enrico Redolfi De Zan, Riccardo Marzolino, Leigh J Sowerby, Anna Tarantini, Paolo Lanzetta, Cesare Miani

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Luca Giovanni LocatelloDepartment of Otorhinolaryngology, Academic Hospital "Santa Maria della Misericordia", Azienda Sanitaria Universitaria Friuli Centrale, Piazzale Santa Maria della Misericordia 15, 33100 Udine, Italy.ORCID 0000-0002-1879-5580
Enrico Redolfi De ZanDepartment of Medicine-Ophthalmology, University of Udine, 33100 Udine, Italy.ORCID 0009-0003-9379-2704
Riccardo MarzolinoDepartment of Otorhinolaryngology, Academic Hospital "Santa Maria della Misericordia", Azienda Sanitaria Universitaria Friuli Centrale, Piazzale Santa Maria della Misericordia 15, 33100 Udine, Italy.
Leigh J SowerbyDepartment of Otolaryngology-Head and Neck Surgery, Western University, London, ON N6A 3K7, Canada.ORCID 0000-0002-5825-2759
Anna TarantiniDepartment of Medicine-Ophthalmology, University of Udine, 33100 Udine, Italy.
Paolo LanzettaDepartment of Medicine-Ophthalmology, University of Udine, 33100 Udine, Italy.ORCID 0000-0003-3746-141X
Cesare MianiDepartment of Otorhinolaryngology, Academic Hospital "Santa Maria della Misericordia", Azienda Sanitaria Universitaria Friuli Centrale, Piazzale Santa Maria della Misericordia 15, 33100 Udine, Italy.ORCID 0000-0002-0059-7148

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesBecause of their rarity, lacrimal sac tumors (LSTs) are challenging to diagnose and treat. We herein provide an overview of the recent literature.

methodsA scoping search of the Cochrane library, PubMed and Google Scholar database in the last 5 years was conducted. Three independent reviewers extracted data, and the findings were summarized due to study heterogeneity.

resultsA total of 55 articles were included. LST histology is diverse and there is no commonly accepted staging system. Recent discoveries in their biology are offering new treatment strategies but exclusive endoscopic resections remain feasible in only very limited cases of non-aggressive LSTs.

conclusionLSTs require a high index of suspicion because of their rarity. A histotype-driven treatment plan must be carefully prepared, but complete excision remains the cornerstone of treatment in all cases.

Indexed as

dacryocystectomydacryocystorhinostomylacrimal sac cancerlacrimal sac tumororbital surgerytransnasal endoscopic surgery

Identifiers

PMID41301082
PMCPMC12651659

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.