Evidence map›Paper›PMID 41300995›Full record

ReviewCancers2025

The Role of Transcranial Magnetic Stimulation and Peripheral Magnetic Field Therapy in Chemotherapy-Induced Peripheral Neuropathy: A Narrative Review.

Elena Wernecke, Faten Ragaban, Peter B Rosenquist, Nikhil Jaganathan, William J Healy, Egidio Giacomo Del Fabbro

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elena WerneckeMedical College of Georgia, Augusta, GA 30912, USA.
Faten RagabanDivision of Palliative Medicine, Medical College of Georgia, Augusta, GA 30912, USA.
Peter B RosenquistDepartment of Psychiatry and Health Behavior, Medical College of Georgia, Augusta, GA 30912, USA.
Nikhil JaganathanMedical College of Georgia, Augusta, GA 30912, USA.ORCID 0009-0001-7122-0460
William J HealyDivision of Pulmonary, Critical Care, and Sleep Medicine, Medical College of Georgia, Augusta, GA 30912, USA.ORCID 0000-0003-4515-5041
Egidio Giacomo Del FabbroDivision of Pulmonary, Critical Care, and Sleep Medicine, Medical College of Georgia, Augusta, GA 30912, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemotherapy-induced peripheral neuropathy (CIPN) impairs quality of life and may result in discontinuation of anti-neoplastic therapy. In older patients, CIPN is associated with reduced executive function, more severe pain, comorbidities and polypharmacy. The use of magnetic fields to modulate central and peripheral neurons may offer some benefit for relieving neuropathic pain, with few adverse effects. The evidence of the benefits of using transcranial magnetic stimulation (TMS) or peripheral magnetic stimulation (PMS) in patients with CIPN is evaluated in this narrative review. Improved patient-reported outcomes and more rapid nerve conduction velocities in preliminary trials suggest efficacy in patients with CIPN. The potential for additional, broader applications in CIPN includes biomarkers of progression to chronic neuropathic pain, opioid-sparing benefits, and mitigating associated depression and anxiety. Because magnetic stimulation (MS) is relatively resource intense and time consuming, requiring multiple sessions of therapy, its availability is still limited, and multi-center trials are challenging. Further research with sham-controlled clinical trials, using standardized MS techniques and outcome assessments are needed.

Indexed as

cancer symptomschemotherapy-induced peripheral neuropathyrepetitive transcranial magnetic stimulationtranscranial magnetic stimulation

Identifiers

PMID41300995
PMCPMC12650406

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.