Evidence map›Paper›PMID 41300974›Full record

ReviewCancers2025

Intraoperative Ultrasound in the Management of Rare Lesions Involving the Intradural Extramedullary Spinal Compartment: A Quick, but Effective Helping Hand to Define the Optimal Surgical Strategy.

Alessandro Pesce, Luca Di Carlo, Mauro Palmieri, Federica Novegno, Andrea Iaquinandi, Luca Denaro, Daniele Armocida, Antonio Santoro, Maurizio Salvati, Tamara Ius and 1 more

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Predurotomy intraoperative ultrasound in intradural extramedullary spinal tumor surgery: agreement with preoperative magnetic resonance imaging and correlation with microsurgical findings.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alessandro PesceSystems Medicine Department, University of Rome Tor Vergata, 00133 Rome, Italy.
Luca Di CarloHuman Neuroscience, University of Rome Sapienza, 00185 Rome, Italy.ORCID 0009-0006-5410-0543
Mauro PalmieriHuman Neuroscience, University of Rome Sapienza, 00185 Rome, Italy.ORCID 0000-0001-5131-1392
Federica NovegnoSystems Medicine Department, University of Rome Tor Vergata, 00133 Rome, Italy.
Andrea IaquinandiSystems Medicine Department, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0003-2367-9418
Luca DenaroAcademic Neurosurgery, Department of Neurosciences, University of Padua, 35121 Padua, Italy.ORCID 0000-0002-2529-6149
Daniele ArmocidaNeuroscience Department, University of Turin, 10124 Turin, Italy.
Antonio SantoroHuman Neuroscience, University of Rome Sapienza, 00185 Rome, Italy.
Maurizio SalvatiSystems Medicine Department, University of Rome Tor Vergata, 00133 Rome, Italy.
Tamara IusAcademic Neurosurgery, Department of Neurosciences, University of Padua, 35121 Padua, Italy.ORCID 0000-0003-3741-0639
Alessandro FratiHuman Neuroscience, University of Rome Sapienza, 00185 Rome, Italy.ORCID 0000-0001-8062-614X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intraoperative ultrasound (IOUS) is an increasingly adopted adjunctive intraoperative visualization method in spinal tumor surgery, offering real-time imaging that improves lesion localization, exposure planning, and resection control. This paper focuses on IOUS findings in rare intradural entities (neuroenteric/respiratory cysts, chronic spinal subdural hematoma, tethered cord/scarring, intradural extramedullary hemangioblastomas, and arachnoid cysts) where evidence remains limited. Across these lesions, IOUS typically depicts cysts as anechoic or hypoechoic cavities with definable walls and occasional septations; CSSDH is also delimited by hypoechoic subdural collections bounded by echogenic membranes; hemangioblastomas, as well as circumscribed, homogeneous nodules often with cystic components; and arachnoid webs/cysts with their boundaries and subtle subarachnoid communications. Doppler and micro-Doppler can delineate feeding and draining vessels in highly vascular tumors, while shear wave elastography provides quantitative stiffness changes that support effective detethering. IOUS complements preoperative MRI, shortens exposure, helps tailor bone and dural openings, and allows immediate assessment of residual disease. Taken together, current data and our experience support IOUS as a safe, cost-effective, and versatile intraoperative tool for rare intradural spinal pathology, while underscoring the need for prospective studies to refine sonographic criteria and validate outcome benefits.

Indexed as

arachnoid cysthemangioblastomaintradural extramedullary tumorsintraoperative ultrasound (IOUS)neurenteric cystshear wave elastographyspinal chronic subdural hematomatethered cord syndrome

Identifiers

PMID41300974
PMCPMC12651337

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.