ArticleGenes2025
The G Allele and GG Genotype of the Junctional Cadherin 5 Associated (JCAD) Is a Biomarker Predicting Myocardial Infarction in Slovenian Subjects with Type 2 Diabetes Mellitus.
Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPatients with type 2 diabetes mellitus (T2DM) have a two- to fourfold higher risk of myocardial infarction (MI), yet genetic determinants of this excess risk remain incompletely defined. The
objectivesTo assess whether the rs3739998 polymorphism of
methodsWe performed a retrospective cross-sectional association study of 1471 Slovenian subjects with T2DM: 387 with prior MI and 1084 without clinical evidence of coronary artery disease. Genotyping for
resultsThe GG genotype was more frequently observed in MI cases compared to controls in unadjusted analysis (OR 1.37;
conclusionsIn a Slovenian T2DM cohort, the
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