Evidence map›Paper›PMID 41300813›Full record

ReviewGenes2025

The GNAS Gene: Fibrous Dysplasia, McCune-Albright Syndrome, and Skeletal Structure and Function.

Jake Louis Littman, Wentian Yang, Noah Feder, Amr Kaadan, Ali Amin, Roy K Aaron

Abstract readReview
In one paragraph

Review in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jake Louis LittmanSchool of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.ORCID 0000-0002-7122-2423
Wentian YangDepartment of Orthopedic Surgery, Warren Alpert Medical School, Brown University, Providence, RI 02903, USA.ORCID 0000-0002-2127-6239
Noah FederSchool of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.ORCID 0009-0009-4832-2352
Amr KaadanDepartment of Orthopedic Surgery, Warren Alpert Medical School, Brown University, Providence, RI 02903, USA.
Ali AminDepartment of Pathology and Laboratory Medicine, Warren Alpert Medical School, Brown University, Providence, RI 02903, USA.ORCID 0000-0003-4798-0424
Roy K AaronDepartment of Orthopedic Surgery, Warren Alpert Medical School, Brown University, Providence, RI 02903, USA.ORCID 0000-0002-0745-2267

Funding

The Miriam Hospital N/A
6 · The paper itself

Abstract

McCune-Albright Syndrome (MAS) is a rare mosaic disorder caused by somatic activating mutations of the

Indexed as

Bone and BonesChromograninsFibrous Dysplasia of BoneFibrous Dysplasia, PolyostoticGTP-Binding Protein alpha Subunits, GsHumansMutationPhenotypeChromograninsGNAS protein, humanGTP-Binding Protein alpha Subunits, GsboneFDfibrous dysplasiaGNASMASMcCune–Albright syndromeskeletal structure

Identifiers

PMID41300813
PMCPMC12652566

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.