Evidence map›Paper›PMID 41300799›Full record

ArticleGenes2025

Identification of Male-Specific Markers by Genotyping-by-Sequencing in the Giant Spiny Frog,

Yu Xiao, Yun Xia, Xiaomao Zeng

Abstract read
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yu XiaoChengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610213, China.
Yun XiaChengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610213, China.ORCID 0000-0002-3039-0527
Xiaomao ZengChengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610213, China.

Funding

National Natural Science Foundation of China No. 32170419National Natural Science Foundation of China No. 32270448
6 · The paper itself

Abstract

BACKGROUND/

objectives

methodsThis study employed a genotyping-by-sequencing (GBS) method to identify sex-associated genomic markers and elucidate the sex determination mechanism in the species.

resultsWe obtained 853 candidate sex-specific GBS tags, with 811 tags (95.07%) demonstrating a male heterozygous system (XX/XY). The diagnostic specificity of the nine markers was further demonstrated by PCR analysis across multiple adult individuals from seven distinct geographic populations of the frog. Four sex-specific markers were aligned with the

conclusionsOur results deciphered the genetic mechanisms governing sex determination in

Indexed as

AnuraSex Determination ProcessesAnimalsFemaleGenetic MarkersGenotypeGenotyping TechniquesMaleTranscription FactorsDMRT1 proteinGenetic MarkersTranscription FactorsGBSsex determinationsex differentiationsex-specific markers

Identifiers

PMID41300799
PMCPMC12652585

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.